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A comparative study of dynamic scoring formulas for capture-the-flag competitions

Ho et al. | Aug 30, 2024

A comparative study of dynamic scoring formulas for capture-the-flag competitions

The use of gamification in cybersecurity education, particularly through capture-the-flag competitions, involves scoring challenges based on their difficulty and the number of teams that solve them. The study investigated how changing the scoring formulas affects competition outcomes, predicting that different formulas would alter score distributions.

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Predicting smoking status based on RNA sequencing data

Yang et al. | Aug 30, 2024

Predicting smoking status based on RNA sequencing data
Image credit: Yang and Stanley 2024

Given an association between nicotine addiction and gene expression, we hypothesized that expression of genes commonly associated with smoking status would have variable expression between smokers and non-smokers. To test whether gene expression varies between smokers and non-smokers, we analyzed two publicly-available datasets that profiled RNA gene expression from brain (nucleus accumbens) and lung tissue taken from patients identified as smokers or non-smokers. We discovered statistically significant differences in expression of dozens of genes between smokers and non-smokers. To test whether gene expression can be used to predict whether a patient is a smoker or non-smoker, we used gene expression as the training data for a logistic regression or random forest classification model. The random forest classifier trained on lung tissue data showed the most robust results, with area under curve (AUC) values consistently between 0.82 and 0.93. Both models trained on nucleus accumbens data had poorer performance, with AUC values consistently between 0.65 and 0.7 when using random forest. These results suggest gene expression can be used to predict smoking status using traditional machine learning models. Additionally, based on our random forest model, we proposed KCNJ3 and TXLNGY as two candidate markers of smoking status. These findings, coupled with other genes identified in this study, present promising avenues for advancing applications related to the genetic foundation of smoking-related characteristics.

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Investigating the inhibition of catabolic enzymes for implications in cardiovascular diseases and diabetes

Gandhi et al. | Aug 25, 2024

Investigating the inhibition of catabolic enzymes for implications in cardiovascular diseases and diabetes
Image credit: The authors

Enzymes that metabolize carbohydrates and lipids play a key role in our health, including global health challenges like cardiovascular diseases and diabetes. To learn more about these important enzymes, Gandhi and Gandhi test whether various natural substances (ginger, Aloe vera, lemon, and mint leaves) affect the activity of α-amylase and lipase enzymes.

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Does language familiarity affect typing speed?

Shin et al. | Aug 23, 2024

Does language familiarity affect typing speed?

In cognitive psychology, typed responses are used to assess thinking skills and creativity, but research on factors influencing typing speed is limited. This study examined how language familiarity affects typing speed, hypothesizing that familiarity with a language would correlate with faster typing. Participants typed faster in English than Latin, with those unfamiliar with Latin showing a larger discrepancy between the two languages, though Latin education level did not significantly impact typing speed, highlighting the role of language familiarity in typing performance.

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Solubility of graphite and the efficacy of using its dissolved form as a conductive paste

Kirby et al. | Aug 23, 2024

Solubility of graphite and the efficacy of using its dissolved form as a conductive paste

This study explored the use of graphite's conductivity for circuit boards by creating a conductive paste through exfoliation with organic solvents and sonication. The combination of acetone and sonication was found to be the most effective, producing a high-conductivity paste with desirable properties such as a low boiling point. While not a replacement for wires, this conductive paste has potential applications in electronics and infrastructure, provided that key engineering challenges are addressed.

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Using broad health-related survey questions to predict the presence of coronary heart disease

Chavda et al. | Aug 23, 2024

Using broad health-related survey questions to predict the presence of coronary heart disease

Coronary heart disease (CHD) is the leading cause of death in the U.S., responsible for nearly 700,000 deaths in 2021, and is marked by artery clogging that can lead to heart attacks. Traditional prediction methods require expensive clinical tests, but a new study explores using machine learning on demographic, clinical, and behavioral survey data to predict CHD.

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Adults’ attitudes toward non-alcoholic beer purchases and consumption by children and adolescents

An et al. | Aug 23, 2024

Adults’ attitudes toward non-alcoholic beer purchases and consumption by children and adolescents
Image credit: The authors

Consumption of non-alcoholic beverages, like non-alcoholic beer, is growing in popularity in the United States. These beverages raise important societal questions, such as whether minors should be allowed to purchase or consume non-alcoholic beer. An and An investigate this issue by surveying adults to see if they support minors purchasing and consuming non-alcoholic beer.

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