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Effects of Ocean Acidification on the Photosynthetic Ability of Chaetoceros gracilis in the Monterey Bay

Harvell et al. | Jan 16, 2020

Effects of Ocean Acidification on the Photosynthetic Ability of <i>Chaetoceros gracilis</i> in the Monterey Bay

In this article, Harvell and Nicholson hypothesized that increased ocean acidity would decrease the photosynthetic ability of Chaetoceros gracilis, a diatom prolific in Monterey Bay, because of the usually corrosive effects of carbonic acid on both seashells and cells’ internal structures. They altered pH of algae environments and measured the photosynthetic ability of diatoms over four days by spectrophotometer. Overall, their findings indicate that C. gracilis may become more abundant in Monterey Bay as the pH of the ocean continues to drop, potentially contributing to harmful algal blooms.

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Spider Density Shows Weak Relationship with Vegetation Density

Ryon et al. | Jul 03, 2020

Spider Density Shows Weak Relationship with Vegetation Density

Evidence supports that spiders have many ecological benefits including insect control and predation in the food chain. In this study the authors investigate that whether the percent of vegetation coverage and spider density are correlated. They determine that despite the trend there is no statistically significant correlation.

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Effects of Wi-Fi EMF on Drosophila melanogaster

Anand et al. | Jan 29, 2020

Effects of Wi-Fi EMF on <em>Drosophila melanogaster</em>

While increased access to Wi-Fi has been a great advancement, we have a limited understanding if there are any health effects on animals. In this study, Anand and Anand exposed fruit flies (Drosophila melanogaster) to different concentrations of Wi-Fi electromagnetic fields, and observed effects on their reproduction and survivability.

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In silico modeling of emodin’s interactions with serine/threonine kinases and chitosan derivatives

Suresh et al. | Jan 10, 2022

<i>In silico</i> modeling of emodin’s interactions with serine/threonine kinases and chitosan derivatives

Here, through protein-ligand docking, the authors investigated the effect of the interaction of emodin with serine/threonine kinases, a subclass of kinases that is overexpressed in many cancers, which is implicated in phosphorylation cascades. Through molecular dynamics theyfound that emodin forms favorable interactions with chitosan and chitosan PEG (polyethylene glycol) copolymers, which could aid in loading drugs into nanoparticles (NPs) for targeted delivery to cancerous tissue. Both polymers demonstrated reasonable entrapment efficiencies, which encourages experimental exploration of emodin through targeted drug delivery vehicles and their anticancer activity.

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Potential Multifunctional Agents for Dual Therapy of Age-Related and Associated Diseases: Alzheimer’s Disease and Type 2 Diabetes Mellitus

Kumar et al. | Nov 13, 2019

Potential Multifunctional Agents for Dual Therapy of Age-Related and Associated Diseases: Alzheimer’s Disease and Type 2 Diabetes Mellitus

Studies show an age-related link between Alzheimer’s Disease and Type 2 Diabetes Mellitus with oxidative stress a characteristic of both. Here, methanolic fractionations and extracts of four Ayurvedic plants were assessed for their protective abilities using a number of in vitro assays. Extracts inhibited oxidative stress and reduced activity of key enzymes involved in the pathogenesis of both diseases in neuroblastoma cells.

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The Cilium- and Centrosome-Associated Protein CCDC11 Is Required for Cytokinesis via Midbody Recruitment of the ESCRT- III Membrane Scission Complex Subunit CHMP2A

Ahmed et al. | Mar 14, 2018

The Cilium- and Centrosome-Associated Protein CCDC11 Is Required for Cytokinesis via Midbody Recruitment of the ESCRT- III Membrane Scission Complex Subunit CHMP2A

In order for cells to successfully multiply, a number of proteins are needed to correctly coordinate the replication and division process. In this study, students use fluorescence microscopy and molecular methods to study CCDC11, a protein critical in the formation of cilia. Interestingly, they uncover a new role for CCDC11, critical in the cell division across multiple human cell lines.

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Combating Insulin Resistance Using Medicinal Plants as a Supplementary Therapy to Metformin in 3T3-L1 Adipocytes: Improving Early Intervention-Based Diabetes Treatment

Jayram et al. | Apr 08, 2019

Combating Insulin Resistance Using Medicinal Plants as a Supplementary Therapy to Metformin in 3T3-L1 Adipocytes: Improving Early Intervention-Based Diabetes Treatment

A primary cause of diabetes is insulin resistance, which is caused by disruption of insulin signal transduction. The objective of this study was to maximize insulin sensitivity by creating a more effective, early intervention-based treatment to avert severe T2D. This treatment combined metformin, “the insulin sensitizer”, and medicinal plants, curcumin, fenugreek, and nettle.

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