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Prediction of preclinical Aβ deposit in Alzheimer’s disease mice using EEG and machine learning

Igarashi et al. | Nov 29, 2022

Prediction of preclinical Aβ deposit in Alzheimer’s disease mice using EEG and machine learning

Alzheimer’s disease (AD) is a common disease affecting 6 million people in the U.S., but no cure exists. To create therapy for AD, it is critical to detect amyloid-β protein in the brain at the early stage of AD because the accumulation of amyloid-β over 20 years is believed to cause memory impairment. However, it is difficult to examine amyloid-β in patients’ brains. In this study, we hypothesized that we could accurately predict the presence of amyloid-β using EEG data and machine learning.

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Suppress that algae: Mitigating the effects of harmful algal blooms through preemptive detection & suppression

Natarajan et al. | Jul 17, 2023

Suppress that algae: Mitigating the effects of harmful algal blooms through preemptive detection & suppression
Image credit: Sharanya Natarajan

A bottleneck in deleting algal blooms is that current data section is manual and is reactionary to an existing algal bloom. These authors made a custom-designed Seek and Destroy Algal Mitigation System (SDAMS) that detects harmful algal blooms at earlier time points with astonishing accuracy, and can instantaneously suppress the pre-bloom algal population.

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A Novel Method for Auto-Suturing in Laparoscopic Robotic-Assisted Coronary Artery Bypass Graft (CABG) Anastomosis

Levy et al. | Jun 21, 2018

A Novel Method for Auto-Suturing in Laparoscopic Robotic-Assisted Coronary Artery Bypass Graft (CABG) Anastomosis

Levy & Levy tackle the optimization of the coronary artery bypass graft, a life-saving surgical technique that treats artery blockage due to coronary heart disease. The authors develop a novel auto-suturing method that saves time, allows for an increased number of sutures, and improves graft quality over hand suturing. The authors also show that increasing the number of sutures from four to five with their new method significantly improves graft quality. These promising findings may help improve outcomes for patients undergoing surgery to treat coronary heart disease.

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Interleukin family (IL-2 and IL-1β) as predictive biomarkers in Indian cancer patients: A proof of concept study

Parthasarathy et al. | Apr 03, 2023

Interleukin family (IL-2 and IL-1β) as predictive biomarkers in Indian cancer patients: A proof of concept study
Image credit: National Cancer Institute

Here, recognizing that the immune response to cancer results in biomarkers that can be used to assess the immune status of cancer patients, the authors investigated the concentrations of key cytokines (TH1 and TH2 cytokines) in healthy controls and cancer patients. They identified significant changes in resting and activated cytokine profiles, suggesting that data of biomarkers such as these could serve as a starting point for further treatment with regard to a patient's specific immune profile.

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How does light affect the distribution of Euglena sp. and Tetrahymena pyriformis

Singh et al. | Mar 03, 2022

How does light affect the distribution of <em>Euglena sp.</em> and <em>Tetrahymena pyriformis</em>

In this article, the authors explored the locomotory movement of Euglena sp. and Tetrahymena pyriformis in response to light. Such research bears relevance to the migration and distribution patterns of both T. pyriformis and Euglena as they differ in their method of finding sustenance in their native environments. With little previous research done on the exploration of a potential response to photostimulation enacted by T. pyriformis, the authors found that T. pyriformis do not bias in distribution towards areas of light - unlike Euglena, which displayed an increased prevalence in areas of light.

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Osmotic characteristics of water retention structures of Bursera microphylla in relation to soil salinity

Groom et al. | Jul 12, 2023

Osmotic characteristics of water retention structures of <i>Bursera microphylla</i> in relation to soil salinity
Image credit: Lisa Fotios

This study hypothesized that sodium chloride was taken up through plant root structures to facilitate water transportation, and that sodium chloride accumulation was directly proportional to the soil salinity. Results showed that most cells within the “bulb” structures were isotonic at a concentration approximately twice as high as that of root tissue and ambient soil salinity, therefore supporting the presented hypothesis.

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