Browse Articles

The impact of greenhouse gases, regions, and sectors on future temperature anomaly with the FaIR model

Kosaraju et al. | Jul 29, 2024

The impact of greenhouse gases, regions, and sectors on future temperature anomaly with the FaIR model

This study explores how different economic sectors, geographic regions, and greenhouse gas types might affect future global mean surface temperature (GMST) anomalies differently from historical patterns. Using the Finite Amplitude Impulse Response (FaIR) model and four Shared Socioeconomic Pathways (SSPs) — SSP126, SSP245, SSP370, and SSP585 — the research reveals that future contributions to GMST anomalies.

Read More...

Mathematical modeling of plant community composition for urban greenery plans

Fang et al. | Jul 05, 2023

Mathematical modeling of plant community composition for urban greenery plans
Image credit: CHUTTERSNAP

Here recognizing the importance of urban green space for the health of humans and other organisms, the authors investigated if mathematical modeling can be used to develop an urban greenery management plan with high eco-sustainability by calculating the composition of a plant community. They optimized and tested their model against green fields in a Beijing city park. Although the compositions predicted by their models differed somewhat from the composition of testing fields, they conclude that by using a mathematical model such as this urban green space can be finely designed to be ecologically and economically sustainable.

Read More...

Homology modeling of clinically-relevant rilpivirine-resistant HIV-RT variants identifies novel rilpivirine analogs with retained binding affinity against NNRTI-resistant HIV mutations

Luk et al. | Jan 24, 2022

Homology modeling of clinically-relevant rilpivirine-resistant HIV-RT variants identifies novel rilpivirine analogs with retained binding affinity against NNRTI-resistant HIV mutations

Human immunodeficiency virus (HIV), which affects tens of millions of individuals worldwide, can lead to acquired immunodeficiency syndrome (AIDS). While there is currently no cure for HIV, the development of small molecule antiretroviral agents has greatly improved the prognosis of infected individuals, especially in developed countries. Here, the authors employ homology modeling and molecular docking towards the identification of novel rilpivirine analogs that retain high binding affinity to clinically relevant rilpivirine-resistant mutations of the HIV reverse transcriptase enzyme.

Read More...

Assessing machine learning model efficacy for brain tumor MRI classification: a multi-model approach

Dhingra et al. | Mar 14, 2026

Assessing machine learning model efficacy for brain tumor MRI classification: a multi-model approach
Image credit: Dhingra and Dhingra

This manuscript explores the performance of five different machine learning models in classifying brain tumors from a dataset of MRI scans. The authors find that several of the models showed >90% accuracy. Thus, the authors suggest that machine learning models demonstrate potential for effective implementation in clinical settings, including as a diagnostic tool that can be used to complement the expertise of neuroradiologists.

Read More...