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The effect of activation function choice on the performance of convolutional neural networks

Wang et al. | Sep 15, 2023

The effect of activation function choice on the performance of convolutional neural networks
Image credit: Tara Winstead

With the advance of technology, artificial intelligence (AI) is now applied widely in society. In the study of AI, machine learning (ML) is a subfield in which a machine learns to be better at performing certain tasks through experience. This work focuses on the convolutional neural network (CNN), a framework of ML, applied to an image classification task. Specifically, we analyzed the performance of the CNN as the type of neural activation function changes.

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Cell cytotoxicity and pro-apoptosis on MCF-7 cells using polyherbal formulation, MAT20

Tarigopula et al. | Feb 17, 2023

Cell cytotoxicity and pro-apoptosis on MCF-7  cells using polyherbal formulation, MAT20

The purpose of this study was to test the anti-cancer properties and pro-apoptotic effects of the polyherbal formulation MAT20 as a complementary treatment. Moringa oleifera (Moringa), Phyllanthus emblica (Amla) and Ocimum sanctum (Tulsi), these 3 herbs were used to formulate MAT20, which contain phytochemicals that are known to display anti-cancer properties. In this study, we hypothesized that MCF-7 breast cancer cells treated with MAT20 would show increased cytotoxicity compared to its individual plant extracts.

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Effect of hypervitaminosis A in regenerating planaria: A potential model for teratogenicity testing

Bennet et al. | Dec 12, 2022

Effect of hypervitaminosis A in regenerating planaria: A potential model for teratogenicity testing

This unique research study evaluated the potential use of the flatworm, brown planaria (Dugesia tigrine), as an alternative model for teratogenicity testing. In this study, we exposed amputated planaria to varying concentrations of a known teratogen, vitamin A (retinol), for approximately 2 weeks, and evaluated multiple parameters including the formation of blastema and eyes. The results from this study demonstrated that high concentrations of retinol caused defects in head and eye formation in regenerating planaria, with similarities to vitamin A related teratogenicity findings in mammals. Based on these results, regenerating brown planaria are a promising alternative model for teratogenicity testing, which can potentially be paradigm shifting as it can reduce cost, time, and pregnant animal use in research.

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COVID 19 and the perceived impacts on adolescents’ and young adults’ mental health: A quantitative survey

Kumar et al. | Jul 31, 2023

COVID 19 and the perceived impacts on adolescents’ and young adults’ mental health: A quantitative survey
Image credit: Nick Fewings

Here, recognizing the effects of the COVID-19 pandemic on young peoples' mental health and wellbeing the authors used an online survey which included the short General Health Questionnaire (GHQ-12) to probe 102 young adults. Overall they found that young adults perceived the pandemic to be detrimental to many areas of their wellbeing, with females and those aged 18-19 and 22-23 reporting to be the most significantly impacted.

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Leveraging E-Waste to Enhance Water Condensation by Effective Use of Solid-state Thermoelectric Cooling

Joshi et al. | Dec 02, 2020

Leveraging E-Waste to Enhance Water Condensation by Effective Use of Solid-state Thermoelectric Cooling

Water scarcity affects upwards of a billion people worldwide today. This project leverages the potential of capturing humidity to build a high-efficiency water condensation device that can generate water and be used for personal and commercial purposes. This compact environment-friendly device would have low power requirements, which would potentially allow it to utilize renewable energy sources and collect water at the most needed location.

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Starts and Stops of Rhythmic and Discrete Movements: Modulation in the Excitability of the Corticomotor Tract During Transition to a Different Type of Movement

Lim et al. | Aug 27, 2018

Starts and Stops of Rhythmic and Discrete Movements: Modulation in the Excitability of the Corticomotor Tract During Transition to a Different Type of Movement

Control of voluntary and involuntary movements is one of the most important aspects of human neurological function, but the mechanisms of motor control are not completely understood. In this study, the authors use transcranial magnetic stimulation (TMS) to stimulate a portion of the motor cortex while subjects performed either discrete (e.g. throwing) or rhythmic (e.g. walking) movements. By recording electrical activity in the muscles during this process, the authors showed that motor evoked potentials (MEPs) measured in the muscles during TMS stimulation are larger in amplitude for discrete movements than for rhythmic movements. Interestingly, they also found that MEPs during transitions between rhythmic and discrete movements were nearly identical and larger in amplitude than those recorded during either rhythmic or discrete movements. This research provides important insights into the mechanisms of neurological control of movement and will serve as the foundation for future studies to learn more about temporal variability in neural activity during different movement types.

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Can Green Tea Alleviate the Effects of Stress Related to Learning and Long-Term Memory in the Great Pond Snail (Lymnaea stagnalis)?

Elias et al. | Jan 30, 2021

Can Green Tea Alleviate the Effects of Stress Related to Learning and Long-Term Memory in the Great Pond Snail (<em>Lymnaea stagnalis</em>)?

Stress and anxiety have become more prevalent issues in recent years with teenagers especially at risk. Recent studies show that experiencing stress while learning can impair brain-cell communication thus negatively impacting learning. Green tea is believed to have the opposite effect, aiding in learning and memory retention. In this study, the authors used Lymnaea stagnalis , a pond snail, to explore the relationship between green tea and a stressor that impairs memory formation to determine the effects of both green tea and stress on the snails’ ability to learn, form, and retain memories. Using a conditioned taste aversion (CTA) assay, where snails are exposed to a sweet substance followed by a bitter taste with the number of biting responses being recorded, the authors found that stress was shown to be harmful to snail learning and memory for short-term, intermediate, and long-term memory.

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Reddit v. Wall Street: Why Redditors beat Wall Street at its own game

Bhakar et al. | Sep 13, 2022

Reddit v. Wall Street: Why Redditors beat Wall Street at its own game

Here the authors investigated the motivation of a short squeeze of GameStop stock where users of the internet forum Reddit drove a sudden increase in GameStop stock price during the start of 2021. They relied on both qualitative and quantitative analyses where they tracked activity on the r/WallStreetBets subreddit in relation to mentions of GameStop. With these methods they found that while initially the short squeeze was driven by financial motivations, later on emotional motivations became more important. They suggest that social phenomena can be dynamic and evolve necessitating mixed method approaches to study them.

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