In this article, the authors quantify fluctuations of primary proteins found within bovine milk across four stages of lactation. Critically, these findings bear great relevance to the nutritional support of calves as well as the varying severity of symptoms of lactose intolerance.
The sequence of nitrogenous bases that make up the DNA of organisms can contain hidden mathematical sequences. Here the authors used BioPython, a programming tool, to find an organism that displays Gijswijt’s Sequence in its genome. In this manner they found that the common carp best displays Gijswijt’s Sequence in its genome.
In this study, the authors ask whether a Tau immunotherapy treatment, Hsp70 protein treatment, or dual treatment approach of both the Tau imunotherapy treatment and Hsp70 protein treatment leads to a greater reduction in Tau protein concentration in Alzheimer's disease. Overall, they conclude that the effectiveness of the treatment ultimately relies on the stage of Alzheimer’s.
Sesame (Sesamum indicum) and moringa (Moringa oleifera) have natural antioxidants that could prevent cancer growth. Previously, this group found that sesame and moringa individually suppress eye tumor grown in the Drosophila melanogaster model. In the present study, combinations of sesame and moringa at different concentrations were included in the D. melanogaster diet. The impact on eye tumor development was assessed at different stages of growth.
The authors investigate whether Western Bluebirds and other perching birds consume eggshells, as a source of calcium, at a greater rate before reproduction and during nest building when they are unable to store calcium.
In this study, the authors investigate the anti-cancer effects of Annona Reticulata (Ramphal or custard apple) by testing whether its extract could inhibit HeLa cell viability.
Despite the prevalence of PD, diagnosing PD is expensive, requires specialized testing, and is often inaccurate. Moreover, diagnosis is often made late in the disease course when treatments are less effective. Using existing voice data from patients with PD and healthy controls, the authors created and trained two different algorithms: one using logistic regression and another employing an artificial neural network (ANN).
This study aimed to determine whether the life cycle stages, or phenophases, of some plants in the urban environment of Central Park, New York, differ from the typical phenophases of the same plant species. The authors hypothesized that the phenophases of the thirteen plants we studied would differ from their typical phenophases due to the urban heat island effect. Although the phenophases of five plants matched up with typical trends, there were distinct changes in the phenophases of the other eight, possibly resulting from the urban heat island effect.
In the battle against Alzheimer's disease, early detection is critical to mitigating symptoms in patients. Here, the authors use a collection of MRI scans, layering with deep learning computer modeling, to investigate early stages of AD which can be hard to catch by human eye. Their model is successful, able to outperform previous models, and detected regions of interest in the brain for further consideration.
Many cases of viral hepatitis are easily preventable if caught early; however, a lack of public awareness regarding often leads to diagnoses near the final stages of disease when it is most lethal. Thus, we wanted to understand to what extent an individual's sex, age, education and country of residence (India or Singapore) impacts disease identification. We sent out a survey and quiz to residents in India (n = 239) and Singapore (n = 130) with questions that test their knowledge and awareness of the disease. We hypothesized that older and more educated individuals would score higher because they are more experienced, but that the Indian population will not be as knowledgeable as the Singaporean population because they do not have as many resources, such as socioeconomic access to schools and accessibility to healthcare, available to them. Additionally, we predicted that there would not be any notable differences between make and females. The results revealed that the accuracy for all groups we looked at was primarily below 50%, demonstrating a severe knowledge gap. Therefore, we concluded that if more medical professionals discussed viral hepatitis during hospital visits and in schools, patients can avoid the end stages of the disease in notable cases.