Heating of DNA-containing solutions is a part of many experiment protocols, but it can also cause damage and degradation of the DNA molecules, potentially leading to error in the experimental results. The authors of this paper investigate whether the presence of certain cations during heating can stabilize the DNA polymer and aid the preservation of the molecule.
Here the authors investigated the optical possibilities of gelatin and acrylic in regards to potential implementations at soft contact lenses. They fabricated lenses of different shapes and evaluated the refraction of laser light finding that gelatin needed to be thickened or increased in curvature to account for its lower refractive index compared to plastics, or used in a mixture to strengthen the lens.
Here, seeking to identify an optimal method to classify tree species through remote sensing, the authors used a few machine learning algorithms to classify forest tree species through multispectral satellite imagery. They found the Random Forest algorithm to most accurately classify tree species, with the potential to improve model training and inference based on the inclusion of other tree properties.
Here, recognizing the recognizing the growing threat of non-biodegradable plastic waste, the authors investigated the ability to use a modified enzyme identified in bacteria to decompose polyethylene terephthalate (PET). They used simulations to screen and identify an optimized enzyme based on machine learning models. Ultimately, they identified a potential mutant PETases capable of decomposing PET with improved thermal stability.
In this study, the authors investigate whether a new compound has anti-cancer properties. Using the crude extract from the Amaranthus spinosus plant, HeLa cancer cells were assessed for cell death. Findings reveal that the extract (AS20) has cytotoxic effects on HeLa cells. Their findings introduce a new compound to potentially pursue in the hunt for novel cancer treatments.
Sound waves can be amazingly powerful, especially when they work together. Here the authors create an “acoustic lens” that focuses sound waves on a single location. This makes the sound waves very powerful, capable of causing damage at a precise point. In the future, acoustic lenses like this could potentially be used to treat cancer by killing small tumors without surgery.
Dye-sensitized solar cells (DSSC) use dye as the photoactive material, which capture the incoming photon of light and use the energy to excite electrons. Research in DSSCs has centered around improving the efficacy of photosensitive dyes. A fruit's color is defined by a unique set of molecules, known as a pigment profile, which changes as a fruit progresses from ripe to rotten. This project investigates the use of fresh and rotten fruit extracts as the photoactive dye in a DSSC.
Here, recognizing the important role of bacterial biofilms in many life-threatening chronic infections, the authors investigated the effectiveness of a combination treatment on biofilms composed of up to three different common species within the lungs of cystic fibrosis patients with computational analysis. They found that a triple cocktail therapy targeting three different signaling pathways has significant potential as both a treatment and prophylaxis.
In this study, the authors investigate a potential case of cross antibiotic-resistance. Using swabs from an individual who received long-term treatments of azithromycin, they addressed the question of whether any bacteria in this individual might develop resistance to not only azithromycin, but also other antibiotics with similar structures. This study cleverly addresses the important issue of antibiotic resistance from a new and thoughtful approach.
Here the authors investigated the relationship between fitness-related social media and the high usage of performance-enhancing drugs (PEDs) specifically by men in the US age 18-35. In a survey with 149 participants they identified that young men that use fitness-related social media are more likely to use PEDs. Their results suggest the necessity to consider potential risk behaviors which may be related to social media consumption.