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Characterizing the association between hippocampal reactive astrogliosis, anhedonia-like behaviors, and neurogenesis in a monkey model of stress and antidepressant treatment

Kim et al. | Aug 25, 2022

Characterizing the association between hippocampal reactive astrogliosis, anhedonia-like behaviors, and neurogenesis in a monkey model of stress and antidepressant treatment

This study examined the effects of stress and selective serotonin reuptake inhibitors (SSRIs) on a measure of astrocyte reactivity in nonhuman primate (NHP) models of stress. Results showed that chronic separation stress in NHPs leads to increased signs of astrogliosis in the NHP hippocampus. The findings were consistent with the hypotheses that hippocampal astrogliosis is an important mechanism in stress-induced cognitive and behavioral deficits.

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Similarity Graph-Based Semi-supervised Methods for Multiclass Data Classification

Balaji et al. | Sep 11, 2021

Similarity Graph-Based Semi-supervised Methods for Multiclass Data Classification

The purpose of the study was to determine whether graph-based machine learning techniques, which have increased prevalence in the last few years, can accurately classify data into one of many clusters, while requiring less labeled training data and parameter tuning as opposed to traditional machine learning algorithms. The results determined that the accuracy of graph-based and traditional classification algorithms depends directly upon the number of features of each dataset, the number of classes in each dataset, and the amount of labeled training data used.

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Assessing machine learning model efficacy for brain tumor MRI classification: a multi-model approach

Dhingra et al. | Mar 14, 2026

Assessing machine learning model efficacy for brain tumor MRI classification: a multi-model approach
Image credit: Dhingra and Dhingra

This manuscript explores the performance of five different machine learning models in classifying brain tumors from a dataset of MRI scans. The authors find that several of the models showed >90% accuracy. Thus, the authors suggest that machine learning models demonstrate potential for effective implementation in clinical settings, including as a diagnostic tool that can be used to complement the expertise of neuroradiologists.

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Groundwater prediction using artificial intelligence: Case study for Texas aquifers

Sharma et al. | Apr 19, 2024

Groundwater prediction using artificial intelligence: Case study for Texas aquifers

Here, in an effort to develop a model to predict future groundwater levels, the authors tested a tree-based automated artificial intelligence (AI) model against other methods. Through their analysis they found that groundwater levels in Texas aquifers are down significantly, and found that tree-based AI models most accurately predicted future levels.

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A machine learning approach for abstraction and reasoning problems without large amounts of data

Isik et al. | Jun 25, 2022

A machine learning approach for abstraction and reasoning problems without large amounts of data

While remarkable in its ability to mirror human cognition, machine learning and its associated algorithms often require extensive data to prove effective in completing tasks. However, data is not always plentiful, with unpredictable events occurring throughout our daily lives that require flexibility by artificial intelligence utilized in technology such as personal assistants and self-driving vehicles. Driven by the need for AI to complete tasks without extensive training, the researchers in this article use fluid intelligence assessments to develop an algorithm capable of generalization and abstraction. By forgoing prioritization on skill-based training, this article demonstrates the potential of focusing on a more generalized cognitive ability for artificial intelligence, proving more flexible and thus human-like in solving unique tasks than skill-focused algorithms.

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