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Phospholipase A2 increases the sensitivity of doxorubicin induced cell death in 3D breast cancer cell models

Lee et al. | Mar 30, 2022

Phospholipase A2 increases the sensitivity of doxorubicin induced cell death in 3D breast cancer cell models

Inefficient penetration of cancer drugs into the interior of the three-dimensional (3D) tumor tissue limits drugs' delivery. The authors hypothesized that the addition of phospholipase A2 (PLA2) would increase the permeability of the drug doxorubicin for efficient drug penetration. They found that 1 mM PLA2 had the highest permeability. Increased efficiency in drug delivery would allow lower concentrations of drugs to be used, minimizing damage to normal cells.

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Machine learning on crowd-sourced data to highlight coral disease

Narayan et al. | Jul 26, 2021

Machine learning on crowd-sourced data to highlight coral disease

Triggered largely by the warming and pollution of oceans, corals are experiencing bleaching and a variety of diseases caused by the spread of bacteria, fungi, and viruses. Identification of bleached/diseased corals enables implementation of measures to halt or retard disease. Benthic cover analysis, a standard metric used in large databases to assess live coral cover, as a standalone measure of reef health is insufficient for identification of coral bleaching/disease. Proposed herein is a solution that couples machine learning with crowd-sourced data – images from government archives, citizen science projects, and personal images collected by tourists – to build a model capable of identifying healthy, bleached, and/or diseased coral.

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Which Diaper is More Absorbent, Huggies or Pampers?

Shramko et al. | Sep 19, 2013

Which Diaper is More Absorbent, Huggies or Pampers?

The authors here investigate the absorbency of two leading brands of diapers. They find that Huggies Little Snugglers absorb over 50% more salt water than Pampers Swaddlers, although both absorb significantly more fluid than what an average newborn can produce.

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Analysis of reduction potentials to determine the most efficient metals for electrochemical cell alternatives

Carroll et al. | Jul 10, 2020

Analysis of reduction potentials to determine the most efficient metals for electrochemical cell alternatives

In this study, the authors investigate what metals make the most efficient electrochemical cells, which are batteries that use the difference in electrical potential to generate electricity. Calculations predicted that a cell made of iron and magnesium would have the highest efficiency. Construction of an electrochemical cell of iron and magnesium produced voltages close to the theoretical voltage predicted. These findings are important as work continues towards making batteries with the highest storage efficiency possible.

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Differences in Reliability and Predictability of Harvested Energy from Battery-less Intermittently Powered Systems

Sampath et al. | Apr 29, 2020

Differences in Reliability and Predictability of Harvested Energy from Battery-less Intermittently Powered Systems

Solar and radio frequency harvesters serve as a viable alternative energy source to batteries in many cases where the battery cannot be easily replaced. Using specifically designed circuit models, the authors quantify the reliability of different harvested energy sources to identify the most practical and efficient forms of renewable energy.

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Geographic Distribution of Scripps National Spelling Bee Spellers Resembles Geographic Distribution of Child Population in US States upon Implementation of the RSVBee “Wildcard” Program

Kannankeril et al. | Aug 17, 2020

Geographic Distribution of Scripps National Spelling Bee Spellers Resembles Geographic Distribution of Child Population in US States upon Implementation of the RSVBee “Wildcard” Program

The Scripps National Spelling Bee (SNSB) is an iconic academic competition for United States (US) schoolchildren, held annually since 1925. However, the sizes and geographic distributions of sponsored regions are uneven. One state may send more than twice as many spellers as another state, despite similar numbers in child population. In 2018, the SNSB introduced a wildcard program known as RSVBee, which allowed students to apply to compete as a national finalist, even if they did not win their regional spelling bee. In this study, the authors tested the hypothesis that the geographic distribution of SNSB national finalists more closely matched the child population of the US after RSVBee was implemented.

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Comparative analysis of CO2 emissions of electric ride-hailing vehicles over conventional gasoline personal vehicles

Raman et al. | Jan 12, 2024

Comparative analysis of CO<sub>2</sub> emissions of electric ride-hailing vehicles over conventional gasoline personal vehicles
Image credit: Paul Hanaoka

While some believe that ride-hailing services offer reduced CO2 emissions compared to individual driving, studies have found that driving without passengers on ride-hailing trips or "deadheading" prevents this. Here, with a mathematical model, the authors investigated if the use of electric vehicles as ride-hailing vehicles could offer reduced CO2 emissions. They found that the improved vehicle efficiency and cleaner generation could in fact lower emissions compared to the use of personal gas vehicles.

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Testing Epoxy Strength: The High Strength Claims of Selleys’s Araldite Epoxy Glues

Nguyen et al. | Jul 14, 2020

Testing Epoxy Strength: The High Strength Claims of Selleys’s Araldite Epoxy Glues

Understanding the techniques used to improve the adhesion strength of the epoxy resin is important especially for consumer applications such as repairing car parts, bonding aluminum sheeting, and repairing furniture or applications within the aviation or civil industry. Selleys Araldite epoxy makes specific strength claims emphasizing that the load or weight that can be supported by the adhesive is 72 kg/cm2. Nguyen and Clarke aimed to test the strength claims of Selley’s Araldite Epoxy by gluing two steel adhesion surfaces: a steel tube and bracket. Results showed that there is a lack of consideration by Selleys for adhesion loss mechanisms and environmental factors when accounting for consumer use of the product leading to disputable claims.

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The Prevalence of White Guilt Among American High School Students

Buadu et al. | Jun 03, 2014

The Prevalence of White Guilt Among American High School Students

Racial inequality has been a major issue throughout the history of the United States. In recent years, however, especially with the election of America's first black president, many have claimed that we have made progress and are moving towards a post-racial society. The authors of this study sought to test that claim by evaluating whether high school age students still experience a phenomenon known as white guilt. White guilt is defined as remorse or shame felt by people of Caucasian descent about racial inequality.

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Presence of Vegetation in Relation to Slope in Yosemite Valley, California

Saltzgaber et al. | Sep 11, 2021

Presence of Vegetation in Relation to Slope in Yosemite Valley, California

This study examined the relationship between the slope of a terrain and vegetation, measured by the normalized difference vegetation index (NDVI). It was hypothesized that lower slope ranges would be more supportive of vegetation growth than higher slope ranges. Analysis showed that no slope (even as extreme as 85–90°) prohibits the growth of vegetation completely; even the steepest slopes examined contain plant life. Knowing that steep slopes can still support plant life, agriculturalists can begin to explore and start planting additional crops and plants at these extreme slopes.

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