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Applying centrality analysis on a protein interaction network to predict colorectal cancer driver genes

Saha et al. | Nov 18, 2023

Applying centrality analysis on a protein interaction network to predict colorectal cancer driver genes

In this article the authors created an interaction map of proteins involved in colorectal cancer to look for driver vs. non-driver genes. That is they wanted to see if they could determine what genes are more likely to drive the development and progression in colorectal cancer and which are present in altered states but not necessarily driving disease progression.

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The effect of the consumption of the probiotic B. infantis on ethanol withdrawal symptoms in planaria (Dugesia dorotocephala)

McCandless et al. | Mar 16, 2021

The effect of the consumption of the probiotic B. infantis on ethanol withdrawal symptoms in planaria (Dugesia dorotocephala)

Alcohol use disorder is a chronic, relapsing disease that affects millions of Americans every day. There are limited treatment options for alcohol dependence and alcohol withdrawal symptoms, including depression and anxiety. Previous studies have shown that probiotics can decrease depression in rodents during maternal separation and anxiety in humans. Therefore, we hypothesized that the ethanol-withdrawn planaria who consumed probiotics would have decreased withdrawal symptoms as measured by increased motility compared to the ethanol-withdrawn planaria that were not fed probiotics. The ethanol-withdrawn planaria had a statistically significant decrease in motility compared to the control group, while the planaria that consumed probiotics had no statistically significant change in motility compared to the control group.

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The optical possibilities of gelatin

Parikh et al. | Mar 28, 2024

The optical possibilities of gelatin
Image credit: Lensabl

Here the authors investigated the optical possibilities of gelatin and acrylic in regards to potential implementations at soft contact lenses. They fabricated lenses of different shapes and evaluated the refraction of laser light finding that gelatin needed to be thickened or increased in curvature to account for its lower refractive index compared to plastics, or used in a mixture to strengthen the lens.

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Effects of an Informational Waste Management App on a User’s Waste Disposal Habits

Rao et al. | Apr 28, 2021

Effects of an Informational Waste Management App on a User’s Waste Disposal Habits

While 75% of waste in the United States is stated to be recyclable, only about 34% truly is. This project takes a stance to combat the pillars of mismanaged waste through a modern means of convenience: the TracedWaste app. The purpose of this study was to identify how individuals' waste disposal habits improved and knowledge increased (i.e. correctly disposing of waste, understanding negative incorrect waste disposal) due to their use of an informational waste management app as measured by a survey using a 1-5 Likert Scale. The results showed that the TracedWaste app helped conserve abundant resources such as energy and wood, decrease carbon emissions, and minimize financial toll all through reducing individual impact.

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Analysis of Patterns in the Harmonics of a String with Artificially Enforced Nodes

Jain et al. | Jan 28, 2021

Analysis of Patterns in the Harmonics of a String with Artificially Enforced Nodes

This study examines the higher harmonics in an oscillating string by analyzing the sound produced by a guitar with a spectrum analyzer. The authors mathematically hypothesized that the higher harmonics in the series of the directly excited 2nd harmonic contain the alternate frequencies of the fundamental series, the higher harmonics of the directly excited 3rd harmonic series contain every third frequency of fundamental series, and so on. To test the hypotheses, they enforced artificial nodes to excite the 2nd, 3rd, and 4th harmonics directly, and analyzed the resulting spectrum to verify the mathematical hypothesis. The data analysis corroborates both hypotheses.

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The Effect of Cooking Method on the Amount of Fat in an Egg

Srinivasan et al. | Dec 01, 2014

The Effect of Cooking Method on the Amount of Fat in an Egg

Fat can be chemically altered during cooking through a process called lipid oxidation, which can have a negative impact on health. In this study, the authors measured the extracted fat in raw, fried and hard-boiled eggs and found that cooking eggs to a higher temperature resulted in a lower amount of extracted fat, indicating a greater amount of oxidized fat.

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Estimation of Reproduction Number of Influenza in Greece using SIR Model

Skarpeti et al. | Nov 18, 2020

Estimation of Reproduction Number of Influenza in Greece using SIR Model

In this study, we developed an algorithm to estimate the contact rate and the average infectious period of influenza using a Susceptible, Infected, and Recovered (SIR) epidemic model. The parameters in this model were estimated using data on infected Greek individuals collected from the National Public Health Organization. Our model labeled influenza as an epidemic with a basic reproduction value greater than one.

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Which fruit peel helps retain the most soil moisture?

Parashar et al. | Jan 09, 2024

Which fruit peel helps retain the most soil moisture?
Image credit: Anshu A

Here, the authors investigated the ability to use fruit peels to help soil retain moisture, a property that is essential to agriculture. Across a 96-hour observation period, orange, banana, and kiwi peel water emulsions were evaluated for their effects on soil moisture. They found that orange peels retained the most moisture, but banana and kiwi peels also offered improvements over their control sample.

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The characterization of quorum sensing trajectories of Vibrio fischeri using longitudinal data analytics

Abdel-Azim et al. | Dec 16, 2023

The characterization of quorum sensing trajectories of <i>Vibrio fischeri</i> using longitudinal data analytics

Quorum sensing (QS) is the process in which bacteria recognize and respond to the surrounding cell density, and it can be inhibited by certain antimicrobial substances. This study showed that illumination intensity data is insufficient for evaluating QS activity without proper statistical modeling. It concluded that modeling illumination intensity through time provides a more accurate evaluation of QS activity than conventional cross-sectional analysis.

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Assessing the Efficacy of NOX Enzyme Inhibitors as Potential Treatments for Ischemic Stroke in silico

Vinay et al. | Sep 18, 2020

Assessing the Efficacy of NOX Enzyme Inhibitors as Potential Treatments for Ischemic Stroke <i>in silico</i>

Ischemic stroke occurs when blood flow to the brain is interrupted, causing brain damage. This study investigated the effectiveness of different NOX inhibitors as treatments for ischemic stroke in silico. The results help corroborate previous in vivo and in vitro studies in an in silico format, and can be used towards developing drugs to treat ischemic stroke.

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