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Propagation of representation bias in machine learning

Dass-Vattam et al. | Jun 10, 2021

Propagation of representation bias in machine learning

Using facial recognition as a use-case scenario, we attempt to identify sources of bias in a model developed using transfer learning. To achieve this task, we developed a model based on a pre-trained facial recognition model, and scrutinized the accuracy of the model’s image classification against factors such as age, gender, and race to observe whether or not the model performed better on some demographic groups than others. By identifying the bias and finding potential sources of bias, his work contributes a unique technical perspective from the view of a small scale developer to emerging discussions of accountability and transparency in AI.

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Breast cancer mammographic screening by different guidelines among women of different races/ethnicities

Wang et al. | Aug 27, 2023

Breast cancer mammographic screening by different guidelines among women of different races/ethnicities

Mammographic screening is a common diagnostic tool for breast cancer among average-risk women. The authors hypothesized that adherence rates for mammographic screening may be lower among minorities (non-Hispanic black (NHB) and Hispanic/Latino) than among non-Hispanic whites (NHW) regardless of the guideline applied. The findings support other studies’ results that different racial/ethnic and socio-demographic factors can affect screening adherence. Therefore, healthcare providers should promote breast cancer screening especially among NHW/Hispanic women and women lacking insurance coverage.

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The Inhibitory Effect of Probiotics on the Growth and Biofilm Formation of Salmonella Sp.

Lee et al. | Jan 26, 2019

The Inhibitory Effect of Probiotics on the Growth and Biofilm Formation of Salmonella Sp.

Salmonella is a genus of bacteria responsible for over 90 million cases of intestinal illnesses yearly. Like many bacteria, Salmonella can create a biofilm matrix, which confers stronger resistance against antibiotics. However, there has been relatively little research on the inhibition of Salmonella biofilm formation, which is a crucial factor in its widespread growth. In this study, Lee and Kim quantitatively measure the effectiveness of several common probiotics in inhibiting Salmonella bacterial growth. They found concentration-dependent antibacterial effects varied among the probiotics tested, indicating the possibility of probiotic species-specific mechanisms of Salmonella growth inhibition.

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Development of a Novel Treatment Strategy to Treat Parkinsonian Neurodegeneration by Targeting Both Lewy Body Aggregation and Dopaminergic Neuronal Degradation in a Drosophila melanogaster Model

Sama et al. | Sep 25, 2019

Development of a Novel Treatment Strategy to Treat Parkinsonian Neurodegeneration by Targeting Both Lewy Body Aggregation and Dopaminergic Neuronal Degradation in a <em>Drosophila melanogaster</em> Model

In this article the authors address the complex and life quality-diminishing neurodegenerative disease known as Parkinson's. Although genetic and/or environmental factors contribute to the etiology of the disease, the diagnostic symptoms are the same. By genetically modifying fruit flies to exhibit symptoms of Parkinson's disease, they investigate whether drugs that inhibit mitochondrial calcium uptake or activate the lysosomal degradation of proteins could improve the symptoms of Parkinson's these flies exhibit. The authors report the most promising outcome to be that when both types of drugs were used together. Their data provides encouraging evidence to support further investigation of the utility of such drugs in the treatment of human Parkinson's patients.

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Testing Simarouba amara’s therapeutic effects against weedicide-induced tumor-like morphology in planarians

Thiagarajan et al. | Apr 26, 2024

Testing Simarouba amara’s therapeutic effects against weedicide-induced tumor-like morphology in planarians

According to the World Health Organization, cancer is a leading cause of death globally. The disease’s prevalence is rapidly increasing in association with factors including the increased use of pesticides and herbicides, such as glyphosate, which is one of the most widely used herbicide ingredients. Natural antioxidants and phytochemicals are being tested as anti-cancer agents due to their antiproliferative, antioxidative, and pro-apoptotic properties. Thus, we aimed to investigate the potential role of S. amara extract as a therapeutic agent against glyphosate-induced toxicity and tumor-like morphologies in regenerating and homeostatic planaria (Dugesia dorotocephala).

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Harvesting Atmospheric Water

Greenwald et al. | Jul 10, 2020

Harvesting Atmospheric Water

The objective of this project was to test various materials to determine which ones collect the most atmospheric water when exposed to the same environmental factors. The experiment observed the effect of weather conditions, a material’s surface area and hydrophilicity on atmospheric water collection. The initial hypothesis was that hydrophobic materials with the greatest surface area would collect the most water. The materials were placed in the same outside location each night for twelve trials. The following day, the materials were weighed to see how much water each had collected. On average, ribbed plastic collected 10.8 mL of water per trial, which was over 20% more than any other material. This result partially supported the hypothesis because although hydrophobic materials collected more water, surface area did not have a significant effect on water collection.

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Effect of Gram-positive bacteria on antibiotic resistance in Gram-negative bacteria

Willem et al. | Mar 12, 2024

Effect of Gram-positive bacteria on antibiotic resistance in Gram-negative bacteria

Antibiotics are one of the most common treatments for bacterial infections, but the emergence of antibiotic resistance is a major threat to the control of infectious diseases. Many factors contribute to the development of antibiotic resistance. One is bacterial conjugation from Gram-positive to Gram-negative bacteria where there is a transfer of resistance genes from Gram-positive to Gram-negative bacteria that could increase antibiotic resistance in the latter. In light of these observations, we decided to test whether Gram-negative bacteria that came into contact with Gram-positive bacteria had a higher resistance to the antimicrobial properties of spices than Gram-negative bacteria that did not come into contact with Gram-positive bacteria.

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Role of Environmental Conditions on Drying of Paint

Aggarwal et al. | Feb 20, 2021

Role of Environmental Conditions on Drying of Paint

Reducing paint drying time is an important step in improving production efficiency and reducing costs. The authors hypothesized that decreased humidity would lead to faster drying, ultraviolet (UV) light exposure would not affect the paint colors differently, white light exposure would allow for longer wavelength colors to dry at a faster rate than shorter wavelength colors, and substrates with higher roughness would dry slower. Experiments showed that trials under high humidity dried slightly faster than trials under low humidity, contrary to the hypothesis. Overall, the paint drying process is very much dependent on its surrounding environment, and optimizing the drying process requires a thorough understanding of the environmental factors and their interactive effects with the paint constituents.

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Varying Growth Hormone Levels in Chondrocytes Increases Proliferation Rate and Collagen Production by a Direct Pathway

Bennett et al. | Sep 03, 2019

Varying Growth Hormone Levels in Chondrocytes Increases Proliferation Rate and Collagen Production by a Direct Pathway

Bennett and Joykutty test whether growth hormone directly or indirectly affected the rate at which cartilage renewed itself. Growth hormone could exert a direct effect on cartilage or chondrocytes by modifying the expression of different genes, whereas an indirect effect would come from growth hormone stimulating insulin-like growth factor. The results from this research support the hypothesis that growth hormone increases proliferation rate using the direct pathway. This research can be used in the medical sciences for people who suffer from joint damage and other cartilage-related diseases, since the results demonstrated conditions that lead to increased proliferation of chondrocytes. These combined results could be applied in a clinical setting with the goal of allowing patient cartilage to renew itself at a faster pace, therefore keeping those patients out of pain from these chondrocyte-related diseases.

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Testing Epoxy Strength: The High Strength Claims of Selleys’s Araldite Epoxy Glues

Nguyen et al. | Jul 14, 2020

Testing Epoxy Strength: The High Strength Claims of Selleys’s Araldite Epoxy Glues

Understanding the techniques used to improve the adhesion strength of the epoxy resin is important especially for consumer applications such as repairing car parts, bonding aluminum sheeting, and repairing furniture or applications within the aviation or civil industry. Selleys Araldite epoxy makes specific strength claims emphasizing that the load or weight that can be supported by the adhesive is 72 kg/cm2. Nguyen and Clarke aimed to test the strength claims of Selley’s Araldite Epoxy by gluing two steel adhesion surfaces: a steel tube and bracket. Results showed that there is a lack of consideration by Selleys for adhesion loss mechanisms and environmental factors when accounting for consumer use of the product leading to disputable claims.

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