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Mutation of the Catalytic Cysteine in Anopheles gambiae Transglutaminase 3 (AgTG3) Abolishes Plugin Crosslinking Activity without Disrupting Protein Folding Properties

Pham et al. | May 02, 2014

Mutation of the Catalytic Cysteine in <em>Anopheles gambiae</em> Transglutaminase 3 (AgTG3) Abolishes Plugin Crosslinking Activity without Disrupting Protein Folding Properties

Malaria is a major public health issue, especially in developing countries, and vector control is a major facet of malaria eradication efforts. Recently, sterile insect technique (SIT), or the release of sterile mosquitoes into the wild, has shown significant promise as a method of keeping vector populations under control. In this study, the authors investigate the Anopheles gambiae transglutaminase 3 protein (AgT3), which is essential to the mating of the Anopheles mosquito. They show that an active site mutation is able to abolish the activity of the AgT3 enzyme and propose it as a potential target for chemosterilant inhibitors.

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A Study on the Coagulating Properties of the M. oleifera Seed

Lakshmanan et al. | Feb 14, 2020

A Study on the Coagulating Properties of the <em>M. oleifera</em> Seed

In this study, the authors investigate whether Moringa Oleifera seeds can serve as material to aid in purifying water. M. oleifera seeds have coagulating properties and the authors hypothesized that including it in a water filtration system would reduce particles, specifically bacteria, in water. Their results show that this system removed the largest percent of bacteria. When used in combination with cilantro, it was actually more efficient than the other techniques! These findings have important implications for creating better and more economical water purification systems.

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Augmented Reality Chess Analyzer (ARChessAnalyzer): In-Device Inference of Physical Chess Game Positions through Board Segmentation and Piece Recognition using Convolutional Neural Networks

Mehta et al. | Jul 17, 2020

Augmented Reality Chess Analyzer (ARChessAnalyzer): In-Device Inference of Physical Chess Game Positions through Board Segmentation and Piece Recognition using Convolutional Neural Networks

In this study the authors develop an app for faster chess game entry method to help chess learners improve their game. This culminated in the Augmented Reality Chess Analyzer (ARChessAnalyzer) which uses traditional image and vision techniques for chess board recognition and Convolutional Neural Networks (CNN) for chess piece recognition.

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Comparing Suturing And Stapling In Coronary Bypass Grafting Anastomosis

Levy et al. | Oct 13, 2014

Comparing Suturing And Stapling In Coronary Bypass Grafting Anastomosis

Coronary artery bypass grafts are a common technique to treat coronary heart disease. The authors compared the efficacy of suturing and stapling techniques using an artificial heart pump and silicone tubing and found that suturing, while more time and skill intensive, held pressure in the tubing better than stapling.

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An Analysis of Soil Microhabitats in Revolutionary War, Civil War, and Modern Graveyards on Long Island, NY

Caputo et al. | May 05, 2019

An Analysis of Soil Microhabitats in Revolutionary War, Civil War, and Modern Graveyards on Long Island, NY

Previously established data indicate that cemeteries have contributed to groundwater and soil pollution, as embalming fluids can impact the microbiomes that exist in decomposing remains. In this study, Caputo et al hypothesized that microbial variation would be high between cemeteries from different eras due to dissimilarities between embalming techniques employed, and furthermore, that specific microbes would act as an indication for certain contaminants. Overall, they found that there is a variation in the microbiomes of the different eras’ cemeteries according to the concentrations of the phyla and their more specific taxa.

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Automated classification of nebulae using deep learning & machine learning for enhanced discovery

Nair et al. | Feb 01, 2024

Automated classification of nebulae using deep learning & machine learning for enhanced discovery

There are believed to be ~20,000 nebulae in the Milky Way Galaxy. However, humans have only cataloged ~1,800 of them even though we have gathered 1.3 million nebula images. Classification of nebulae is important as it helps scientists understand the chemical composition of a nebula which in turn helps them understand the material of the original star. Our research on nebulae classification aims to make the process of classifying new nebulae faster and more accurate using a hybrid of deep learning and machine learning techniques.

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The Role of a Mask - Understanding the Performance of Deep Neural Networks to Detect, Segment, and Extract Cellular Nuclei from Microscopy Images

Dasgupta et al. | Jul 06, 2021

The Role of a Mask - Understanding the Performance of Deep Neural Networks to Detect, Segment, and Extract Cellular Nuclei from Microscopy Images

Cell segmentation is the task of identifying cell nuclei instances in fluorescence microscopy images. The goal of this paper is to benchmark the performance of representative deep learning techniques for cell nuclei segmentation using standard datasets and common evaluation criteria. This research establishes an important baseline for cell nuclei segmentation, enabling researchers to continually refine and deploy neural models for real-world clinical applications.

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Predicting college retention rates from Google Street View images of campuses

Dileep et al. | Jan 02, 2024

Predicting college retention rates from Google Street View images of campuses
Image credit: Dileep et al. 2024

Every year, around 40% of undergraduate students in the United States discontinue their studies, resulting in a loss of valuable education for students and a loss of money for colleges. Even so, colleges across the nation struggle to discover the underlying causes of these high dropout rates. In this paper, the authors discuss the use of machine learning to find correlations between the built environment factors and the retention rates of colleges. They hypothesized that one way for colleges to improve their retention rates could be to improve the physical characteristics of their campus to be more pleasing. The authors used image classification techniques to look at images of colleges and correlate certain features like colors, cars, and people to higher or lower retention rates. With three possible options of high, medium, and low retention rates, the probability that their models reached the right conclusion if they simply chose randomly was 33%. After finding that this 33%, or 0.33 mark, always fell outside of the 99% confidence intervals built around their models’ accuracies, the authors concluded that their machine learning techniques can be used to find correlations between certain environmental factors and retention rates.

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Development of Two New Efficient Means of Wastewater Treatment

Bao et al. | Feb 06, 2014

Development of Two New Efficient Means of Wastewater Treatment

The water we use must be treated and cleaned before we release it back into the environment. Here, the authors investigate two new techniques for purifying dissolved impurities from waste water. Their findings may give rise to more cheaper and more efficient water treatment and help keep the planet greener.

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