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The Feasibility of Mixed Reality Gaming as a Tool for Physical Therapy Following a Spinal Cord Injury

DeBre et al. | Apr 04, 2018

The Feasibility of Mixed Reality Gaming as a Tool for Physical Therapy Following a Spinal Cord Injury

Physical therapy, especially for patients with spinal cord injuries, can be a difficult and tedious experience. This can result in negative health outcomes, such as patients dropping out of physical therapy or developing additional health problems. In this study, the authors develop and test a potential solution to these challenges: a mixed reality game called Skyfarer that replaces a standard physical therapy regimen with an immersive experience that can be shared with their friends and family. The findings of this study suggest that mixed reality games such as Skyfarer could be effective alternatives to conventional physical therapy.

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Mechanistic deconvolution of autoreduction in tetrazolium-based cell viability assays

Tran et al. | Jul 12, 2024

Mechanistic deconvolution of autoreduction in tetrazolium-based cell viability assays

Optical reporters like tetrazolium dyes, exemplified by 5-diphenyl tetrazolium bromide (MTT), are effective tools for quantifying cellular responses under experimental conditions. These dyes assess cell viability by producing brightly-colored formazan dyes when reduced inside active cells. However, certain small molecules, including reducing agents like ascorbic acid, cysteine, and glutathione (GSH), can interfere with MTT assays, potentially compromising accuracy.

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Spectroscopic Kinetic Monitoring and Molecular Dynamics Simulations of Biocatalytic Ester Hydrolysis in Non-Aqueous Solvent

Chen et al. | Dec 20, 2020

Spectroscopic Kinetic Monitoring and Molecular Dynamics Simulations of Biocatalytic Ester Hydrolysis in Non-Aqueous Solvent

Lipases are a common class of enzymes that catalyze the breakdown of lipids. Here the authors characterize the the activity of pancreatic lipase in different organic solvents using a choloremetric assay, as well as using molecular dynamic simulations. They report that the activity of pancreatic lipase in 5% methanol is more than 25% higher than in water, despite enzyme stability being comparable in both solvents. This suggests that, for industrial applications, using pancreatic lipase in 5% methanol solution might increase yield, compared to just water.

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Anonymity Reduces Generosity in High School Students

Vargas-Guerrero et al. | Nov 25, 2019

Anonymity Reduces Generosity in High School Students

The disinterested willingness a person has for helping others is known as altruism. But is this willingness to help others dependent on external factors that make you more or less inclined to be generous? We hypothesized that generosity in adolescents would depend on external factors and that these factors would change the amount of help given. To evaluate altruism and generosity, we conducted non-anonymous and anonymous variations of the dictator game and ultimatum game experiments and explored the role of anonymity, fairness, and reciprocity in high school students.

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Comparing Consumer Personality and Brand Personality: Do Fashion Styles Speak of Who You Are?

Stevenson et al. | Oct 02, 2019

Comparing Consumer Personality and Brand Personality: Do Fashion Styles Speak of Who You Are?

This study investigated how fashion brand personalities are similar to people’s personalities and whether people may prefer a particular clothing brand based on their own personal traits. All together, Stevenson and Scott found that the Big Five Personality Factors are generally not related to participants’ preferred brand personalities. Generally, brands should consider different factors besides the Big Five Personality Factors for identifying potential customers.

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