Cellular senescence plays a key role in aging cells and is attributed to a number of disease and pathology. These authors find that genetic editing of both RPS6KB1 and PPARGC1A revitalizes a human skin fibroblast cell line.
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pH-dependent drug interactions with acid reducing agents
Some cancer treatments lose efficacy when combined with treatments for excessive stomach acid, due to the changes in the stomach environment caused by the stomach acid treatments. Lin and Lin investigate information on oral cancer drugs to see what information is available on interactions of these drugs.
Read More...The correlation between bacteria and colorectal cancer
The authors looked at abundance of bacteria in stool samples from patients with colorectal cancer compared to controls. They found different bacteria that was more prevalent in patients with colorectal cancer as well as bacteria in control patients that may indicate a beneficial gut microbiome.
Read More...Adults’ attitudes toward non-alcoholic beer purchases and consumption by children and adolescents
Consumption of non-alcoholic beverages, like non-alcoholic beer, is growing in popularity in the United States. These beverages raise important societal questions, such as whether minors should be allowed to purchase or consume non-alcoholic beer. An and An investigate this issue by surveying adults to see if they support minors purchasing and consuming non-alcoholic beer.
Read More...Effects of alveolar bone grafts vs. orthognathic surgery on cleft palate speech nasalance: a meta-analysis
Patients with cleft palate frequently struggle with speech issues such as nasal or congested speech. Lin and Parkinson conduct a meta-analysis to determine how two common types of cleft palate repair surgery compare in terms of their effects on patient's speech.
Read More...Evaluation of the causality between testosterone, obesity, and diabetes
The study explored the role of testosterone beyond its well-established effects on male sex characteristics, focusing on its association with non-communicable diseases (NCDs) like obesity and type 2 diabetes (T2D), using Mendelian randomization (MR) analysis on genomic data.
Read More...The effect of youth marijuana use on high-risk drug use: Examining gateway and substitution hypothesis
The authors looked at whether youth use of marijuana related to later high-risk drug use. Using survey data from 2010-2019 they found that youth marijuana use did correlate to an increased risk of high-risk drug use.
Read More...Influenza vaccine effectiveness by age for Influenza A/B viruses between 2011-2020
In this manuscript the authors looked at current vaccine strategies against different strains of influenza. Looking at several factors they found that influenza strain as well as vaccinated age group, among other factors, impact vaccine effectiveness.
Read More...Relating socioeconomic position (SEP) and vaccination with Covid-19 rates in select populations
This article describes the relationship between socioeconomic factors and the extent of how the COVID-19 Pandemic affected communities. Factors such as infection rate, vaccination rate, and economic status were all evaluated within the context of this article.
Read More...Differences in postoperative satisfaction between orthopedic and cosmetic patients
In this study, the authors investigate differences in psychological outcomes from patients who undergo different surgical procedures.
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