Human cytomegalovirus (HCMV) causes serious infections in immunocompromised patients and therapies to inhibit latent HCMV are not developed. Using CRISPR/Cas9, the authors were able to delete an important promoter region in HCMV.
Read More...Using CRISPR technology to inhibit the replication of human cytomegalovirus by deletion of a gene promoter
Human cytomegalovirus (HCMV) causes serious infections in immunocompromised patients and therapies to inhibit latent HCMV are not developed. Using CRISPR/Cas9, the authors were able to delete an important promoter region in HCMV.
Read More...Investigating Lemna minor and microorganisms for the phytoremediation of nanosilver and microplastics
The authors looked at phytoremediation, the process by which plants are used to remove pollutants from our environment, and the ability of Lemna minor to perform phytoremediation in various simulated polluted environments. The authors found that L. minor could remove pollutants from the environment and that the addition of bacteria increased this removal.
Read More...Genetic algorithm based features selection for predicting the unemployment rate of India
The authors looked at using genetic algorithms to look at the Indian labor market and what features might best explain any variation seen. They found that features such as economic growth and household consumption, among others, best explained variation.
Read More...Contribution of environmental factors to genetic variation in the Pacific white-sided dolphin
Here the authors sought to understand the effects of different variables that may be tied to pollution and climate change on genetic variation of Pacific white-sided dolphins, a species that is currently threatened by water pollution. Based on environmental data collected alongside a genetic distance matrix, they found that ocean currents had the most significant impact on the genetic diversity of Pacific white-sided dolphins along the Japanese coast.
Read More...Building an affordable model wave energy converter using a magnet and a coil
Here, seeking to identify a method to locally produce and capture renewable energy in Hawai'i and other island communities, the authors built and tested a small-scale model wave energy converter. They tested various configurations of a floated magnet surrounded by a wire coal, where the motion of the magnet due to a wave results in induction current in the coil. While they identified methods to increase the voltage and current generated, they also found that corrosion results in significant deterioration.
Read More...A chemical and overwintering honey bee apiary field study comparing new and expired amitraz miticide
In this study, the authors test the longevity of a anti-mite compound, amitraz, in commercially-sold strips and the age-dependent efficacy of these strips in preventing honey bee colony collapse by ectoparasitic mite Varroa destructor.
Read More...Protective effect of bromelain and pineapple extracts on UV-induced damage in human skin cells
In this study, the authors tested whether the compound bromelain extracted from pineapples could protect skin cells from UV damage.
Read More...The Potential of Fibroblast Growth Factors to Stimulate Hair Growth In Vitro
Identifying treatments that can stimulate hair growth use could help those struggling with undesirable hair loss. Here, the authors show that Fibroblast Growth Factors can stimulate the division of cells isolated from the mouse hair follicle. Their results suggest that this family of growth factors might be helpful in stimulating hair growth in living animals as well.
Read More...Effect of the Herbal Formulation HF1 on the Expression of PD-L1 in PC3 cells
In this study, Imani et al. investigate whether a new proprietary herbal formulation, HF1, can inhibit expression of immune suppressor protein PD-L1. PD-L1 is a transmembrane protein that can be expressed by cancer cells to assist in their ability to avoid attacks from the immune system. Work from this study demonstrates that HF1 treatment can reduce expression of PD-L1 in cultured cancer cells, implicating HF1 as a potential new cancer therapy.
Read More...An Aqueous Solution Containing Soluble Substances From PVC Char Has No Effect on the Rate of Transformation in E. coli Cells
PVC is a widely used plastic that poses harmful health hazards when burned. In this study, the authors ask whether or not burned PVC (PVC char) affects bacterial transformation.
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