![TNF signaling pathway upregulation as a potential pharmaceutical target for cocaine-addicted individuals](/rails/active_storage/representations/proxy/eyJfcmFpbHMiOnsibWVzc2FnZSI6IkJBaHBBbXNKIiwiZXhwIjpudWxsLCJwdXIiOiJibG9iX2lkIn19--736ec9a679d4dc2e1cf00c658783bc272b0879bb/eyJfcmFpbHMiOnsibWVzc2FnZSI6IkJBaDdCem9MWm05eWJXRjBTU0lJYW5CbkJqb0dSVlE2QzNKbGMybDZaVWtpRFRZd01IZzJNREErQmpzR1ZBPT0iLCJleHAiOm51bGwsInB1ciI6InZhcmlhdGlvbiJ9fQ==--a3b53ba1a0f83efef18f6e75a8d4ce784384bee2/myriam-zilles-KltoLK6Mk-g-unsplash.jpg)
In this article, the authors investigate the RNA expression differences between groups of chronic cocaine abusers and drug-free subjects.
Read More...TNF signaling pathway upregulation as a potential pharmaceutical target for cocaine-addicted individuals
In this article, the authors investigate the RNA expression differences between groups of chronic cocaine abusers and drug-free subjects.
Read More...Misconceptions regarding heart disease are prevalent among american adults and minors
In this study, the authors created a survey to assess misconceptions and knowledge deficits regarding cardiovascular diseases exist among US adults and minors.
Read More...Significance of Tumor Growth Modeling in the Behavior of Homogeneous Cancer Cell Populations: Are Tumor Growth Models Applicable to Both Heterogeneous and Homogeneous Populations?
This study follows the process of single-cloning and the growth of a homogeneous cell population in a superficial environment over the course of six weeks with the end goal of showing which of five tumor growth models commonly used to predict heterogeneous cancer cell population growth (Exponential, Logistic, Gompertz, Linear, and Bertalanffy) would also best exemplify that of homogeneous cell populations.
Read More...Effects of Coolant Temperature on the Characteristics of Soil Cooling Curve
In this article, the authors investigate whether coolant temperature affects soil cooling curves of soil with otherwise identical properties. The coolant temperature is representative of environmental temperature, and the authors hypothesized that differences in this temperature would not affect the freezing temperature of soil. Their findings validated their hypothesis providing helpful information relevant to understanding how frost heaves happen and how to predict their occurrence more accurately.
Read More...Stride Frequency, Body Fat Percentage, and the Amount of Knee Flexion Affect the Race Time of Male Cross Country Runners
Cross country is a popular sport in the U.S. Both athletes and coaches are interested in the factors that make runners successful. In this study, the authors explore the relationship between runners' physical attributes and their race performance.
Read More...Groundwater prediction using artificial intelligence: Case study for Texas aquifers
Here, in an effort to develop a model to predict future groundwater levels, the authors tested a tree-based automated artificial intelligence (AI) model against other methods. Through their analysis they found that groundwater levels in Texas aquifers are down significantly, and found that tree-based AI models most accurately predicted future levels.
Read More...The effects of age on quality of mental health during the COVID-19 pandemic
The impact of age on mental health is a crucial yet understudied aspect of public health. While mental health is gaining recognition as a vital component of overall well-being, its correlation with age remains largely unexplored. In Canada, where the median age has risen significantly over the past half-century, understanding this relationship becomes increasingly pertinent. Researchers hypothesized that older adults would exhibit lower rates of mental health disorders and report better perceived mental health due to increased emotional stability and maturity.
Read More...Investigating Lemna minor and microorganisms for the phytoremediation of nanosilver and microplastics
The authors looked at phytoremediation, the process by which plants are used to remove pollutants from our environment, and the ability of Lemna minor to perform phytoremediation in various simulated polluted environments. The authors found that L. minor could remove pollutants from the environment and that the addition of bacteria increased this removal.
Read More...Administration of Stephania tetrandra to Drosophila melanogaster to create obsessive compulsive disorder model
In this study the authors looked at the extract of Stephania tetrandra and its impact on symptoms related to obsessive compulsive disorder in fruit flies.
Read More...Investigation of unknown causes of uveal melanoma uncovers seven recurrent genetic mutations
Uveal melanoma (UM) is a rare subtype of melanoma but the most frequent primary cancer of the eye in adults. The goal of this study was to research the genetic causes of UM through a comprehensive frequency analysis of base-pair mismatches in patient genomes. Results showed a total of 130 genetic mutations, including seven recurrent mutations, with most mutations occurring in chromosomes 3 and X. Recurrent mutations varied from 8.7% to 17.39% occurrence in the UM patient sample, with all mutations identified as missense. These findings suggest that UM is a recessive heterogeneous disease with selective homozygous mutations. Notably, this study has potential wider significance because the seven genes targeted by recurrent mutations are also involved in other cancers.
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