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Antibacterial Effects of Copper Surfaces

Mulukutla et al. | May 19, 2020

Antibacterial Effects of Copper Surfaces

This study examined the ability of copper and copper alloy surfaces to inhibit bacterial growth, which may be help prevent healthcare-associated infections. The authors exposed two non-pathogenic strains of bacteria to different metal plates for varying degrees of time and measured bacterial growth.

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Purification of Water by Aloe

Sharma et al. | Aug 19, 2016

Purification of Water by Aloe

The authors test the ability of aloe vera gel to purify water of four separate contaminants. Aloe reduced the levels of copper, iron, and phosphate, but not nitrate. Potential applications of this purification system are discussed.

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A Crossover Study Comparing the Effect of a Processed vs. Unprocessed Diet on the Spatial Learning Ability of Zebrafish

Banga et al. | Sep 18, 2022

A Crossover Study Comparing the Effect of a Processed vs. Unprocessed Diet on the Spatial Learning Ability of Zebrafish

The authors compared the short-term effects of processed versus unprocessed food on spatial learning and survival in zebrafish, given the large public concern regarding processed foods. By randomly assigning zebrafish to a diet of brine shrimp flakes (processed) or live brine shrimp (unprocessed), the authors show while there is no immediate effect on a fish's decision process between the two diets, there are significant correlations between improved learning and stress response with the unprocessed diet.

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Genomic Signature Analysis for the Strategic Bioremediation of Polycyclic Aromatic Hydrocarbons in Mangrove Ecosystems in the Gulf of Tonkin

Dao et al. | Jun 27, 2021

Genomic Signature Analysis for the Strategic Bioremediation of Polycyclic Aromatic Hydrocarbons in Mangrove Ecosystems in the Gulf of Tonkin

Engineered bacteria that degrade oil are currently being considered as a safe option for the treatment of oil spills. For this approach to be successful, the bacteria must effectively express oil-degrading genes they uptake as part of an external genoming vehicle called a "plasmid". Using a computational approach, the authors investigate plasmid-bacterium compatibility to find pairs that ensure high levels of gene expression.

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Development and Implementation of Enzymatic and Volatile Compound-based Approaches for Instantaneous Detection of Pathogenic Staphylococcus aureus

Nori et al. | Feb 20, 2021

Development and Implementation of Enzymatic and Volatile Compound-based Approaches for Instantaneous Detection of Pathogenic <i>Staphylococcus aureus</i>

Staphylococcus aureus (S. aureus) has a mortality rate of up to 30% in developing countries. The purpose of this experiment was to determine if enzymatic and volatile compound-based approaches would perform more quickly in comparison to existing S. aureus diagnostic methods and to evaluate these novel methods on accuracy. Ultimately, this device provided results in less than 30 seconds, which is much quicker than existing methods that take anywhere from 10 minutes to 48 hours based on approach. Statistical analysis of accuracy provides preliminary confirmation that the device based on enzymatic and volatile compound-based approaches can be an accurate and time-efficient tool to detect pathogenic S. aureus.

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Analysis of the effects of positive ions and boundary layer temperature at various hypersonic speeds on boundary layer density

Selvakumar et al. | Oct 02, 2020

Analysis of the effects of positive ions and boundary layer temperature at various hypersonic speeds on boundary layer density

This study's goal was to identify the Mach numbers for which electrostatic drag and heat transfer manipulation would be most applicable inside the stratosphere. The experiments were conducted using computational fluid dynamics software. The study demonstrated that, on average, higher Mach speeds resulted in a considerably higher potential decrease in density. The study highlights that further research on the surface charge method is warranted to explore higher hypersonic speeds within the stratosphere.

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Effect of Natural Compounds Curcumin and Nicotinamide on α-synuclein Accumulation in a C. elegans Model of Parkinson’s Disease

Mehrotra et al. | Jan 29, 2018

Effect of Natural Compounds Curcumin and Nicotinamide on α-synuclein Accumulation in a C. elegans Model of Parkinson’s Disease

Parkinson's disease is a neurodegenerative disorder that affects over 10 million people worldwide. It is caused by destruction of dopamine-producing neurons, which results in severe motor and movement symptoms. In this study, the authors investigated the anti-Parkinsonian effects of two natural compounds curcumin and nicotinamide using C. elegans as a model organism.

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The role of xpa-1 and him-1 in UV protection of Caenorhabditis elegans

Tung et al. | Feb 25, 2022

The role of <em>xpa-1</em> and <em>him-1</em> in UV protection of <em>Caenorhabditis elegans</em>

Caenorhabditis elegans xpa-1 and him-1 are orthologs of human XPA and human SMC1A, respectively. Mutations in the XPA are correlated with Xeroderma pigmentosum, a condition that induces hypersensitivity to ultraviolet (UV) radiation. Alternatively, SMC1A mutations may lead to Cornelia de Lange Syndrome, a multi-organ disorder that makes patients more sensitive to UVinduced DNA damage. Both C. elegans genes have been found to be involved in protection against UV radiation, but their combined effects have not been tested when they are both knocked down. The authors hypothesized that because these genes are involved in separate pathways, the simultaneous knockdown of both of these genes using RNA interference (RNAi) in C. elegans will cause them to become more sensitive to UV radiation than either of them knocked down individually. UV protection was measured via the percent survival of C. elegans post 365 nm and 5.4x10-19 joules of UV radiation. The double xpa-1/him-1 RNAi knockdown showed a significantly reduced percent survival after 15 and 30 minutes of UV radiation relative to wild-type and xpa-1 and him-1 single knockdowns. These measurements were consistent with their hypothesis and demonstrated that xpa-1 and him-1 genes play distinct roles in resistance against UV stress in C. elegans. This result raises the possibility that the xpa-1/him-1 double knockdown could be useful as an animal model for studying the human disease Xeroderma pigmentosum and Cornelia de Lange Syndrome.

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