In this study, the authors investigate associations between use of histamine H2 receptor antagonists and suicidal ideation in different age groups.
Read More...Association of depression and suicidal ideation among adults with the use of H2 antagonists
In this study, the authors investigate associations between use of histamine H2 receptor antagonists and suicidal ideation in different age groups.
Read More...Utilizing a novel T1rho method to detect spinal degeneration via magnetic resonance imaging
Spinal degeneration has been linked to critical conditions such as osteoarthritis in adults aged 40+; while this condition is considered to be irreversible, we took interest in magnetic resonance imaging (MRI) for early detection of the condition. Ultimately, our purpose was to determine the effectiveness of a relatively novel T1rho method in the early detection of spinal degeneration, and we hypothesized that the early to mild progression of spinal degeneration would affect T1rho values following an MRI scan.
Read More...Suppress that algae: Mitigating the effects of harmful algal blooms through preemptive detection & suppression
A bottleneck in deleting algal blooms is that current data section is manual and is reactionary to an existing algal bloom. These authors made a custom-designed Seek and Destroy Algal Mitigation System (SDAMS) that detects harmful algal blooms at earlier time points with astonishing accuracy, and can instantaneously suppress the pre-bloom algal population.
Read More...A spatiotemporal analysis of OECD member countries on sugar consumption and labor force participation
In this article the authors look at sugar consumption and the relationship to productivity in the work/labor force.
Read More...Who controls U.S. politics? An analysis of major political endorsements in U.S. midterm elections
The authors analyze political endorsement patterns and impacts from the 2018 and 2020 midterm elections and find that such endorsements may be predictable based on the ideological and demographic factors of the endorser.
Read More...Evaluation of in vitro anti-inflammatory effect of PLAY® on UC-MSCs: A COX-2 expression study
The authors seek to accelerate wound healing by reducing inflammation with a cocktail containing growth factors and bioactive modulators.
Read More...Toxicity of aminomethylphosphonic acid via the Wnt signaling pathway as a novel mechanism
The Wnt signaling pathway, known to coordinate important aspects of cellular homeostasis ranging from differentiation, proliferation, migration, and much more, is dysregulated in many human diseases. This study demonstrates that aminomethylphosphonic acid, which is the main metabolite found in the common herbicide Glyphosate, is toxic to planaria and capable of binding to canonical Wnt proteins.
Read More...Solving a new NP-Complete problem that resembles image pattern recognition using deep learning
In this study, the authors tested the ability and accuracy of a neural net to identify patterns in complex number matrices.
Read More...Reactivity-informed design, synthesis, and Michael addition kinetics of C-ring andrographolide analogs
Here, based on the identification of androgapholide as a potential therapeutic treatment against cancer, Alzheimer's disease, diabetes, and multiple sclerosis, due to its ability to inhibit a signaling pathway in immune system function, the authors sought ways to optimize the natural product human systems by manipulating its chemical structure. Through the semisynthesis of a natural product along with computational studies, the authors developed an understanding of the kinetic mechanisms of andrographolide and semisynthetic analogs in the context of Michael additions.
Read More...Disruptions in protein-protein interactions between HTT, PRPF40B, and MECP2 are involved in Lopes-Maciel-Rodan syndrome
In an extensive study of gene mutations, and their resulting effect on protein-protein interactions, Desai and Stork found that HTT-PRPF40B-MECP2 interactions are weakened with progression of Lopes-Maciel-Rodan syndrome.
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