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Combating Insulin Resistance Using Medicinal Plants as a Supplementary Therapy to Metformin in 3T3-L1 Adipocytes: Improving Early Intervention-Based Diabetes Treatment

Jayram et al. | Apr 08, 2019

Combating Insulin Resistance Using Medicinal Plants as a Supplementary Therapy to Metformin in 3T3-L1 Adipocytes: Improving Early Intervention-Based Diabetes Treatment

A primary cause of diabetes is insulin resistance, which is caused by disruption of insulin signal transduction. The objective of this study was to maximize insulin sensitivity by creating a more effective, early intervention-based treatment to avert severe T2D. This treatment combined metformin, “the insulin sensitizer”, and medicinal plants, curcumin, fenugreek, and nettle.

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A Quantitative Analysis of the Proliferation of Microplastics in Williamston’s Waterways

Schafer et al. | Feb 17, 2019

A Quantitative Analysis of the Proliferation of Microplastics in Williamston’s Waterways

Plastic debris can disrupt marine ecosystems, spread contaminants, and take years to naturally degrade. In this study, Wu et al aim to establish an understanding of the scope of Williamston, Michigan’s microplastics problem, as well as to attempt to find the source of these plastics. Initially, the authors hypothesize that the Williamston Wastewater Treatment Plant was the primary contributor to Williamston’s microplastics pollution. Although they find a general trend of increasing concentrations of microplastics from upstream to downstream, they do not pinpoint the source of Williamston’s microplastics pollution in the present research.

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Evaluation of Tea Extract as an Inhibitor of Oxidative Stress in Prostate Cells

Zhang et al. | Jan 22, 2019

Evaluation of Tea Extract as an Inhibitor of Oxidative Stress in Prostate Cells

One important factor that contributes to human cancers is accumulated damage to cells' DNA due to the oxidative stress caused by free radicals. In this study, the authors investigate the effects of several different tea leaf extracts on oxidative stress in cultured human prostate cells to see if antioxidants in the tea leaves could help protect cells from this type of DNA damage. They found that all four types of tea extract (as well as direct application of the antioxidant EGCG) improved the outcomes for the cultured cells, with white tea extract having the strongest effect. This research suggests that tea extracts and the antioxidants that they contain may have applications in the treatment of the many diseases associated with cellular DNA damage, including cancer.

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Enhancing marine debris identification with convolutional neural networks

Wahlig et al. | Apr 03, 2024

Enhancing marine debris identification with convolutional neural networks
Image credit: The authors

Plastic pollution in the ocean is a major global concern. Remotely Operated Vehicles (ROVs) have promise for removing debris from the ocean, but more research is needed to achieve full effectiveness of the ROV technology. Wahlig and Gonzales tackle this issue by developing a deep learning model to distinguish trash from the environment in ROV images.

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Income mobility and government spending in the United States

Datta et al. | Nov 04, 2023

Income mobility and government spending in the United States
Image credit: CDC via Unsplash

Recent research suggests that the "American Dream" of income mobility may be becoming increasingly hard to obtain. Datta and Schmitz explore the role of government spending in socioeconomic opportunity by determining which state government spending components are associated with increased income mobility.

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Socio-economic and awareness correlates of physical activity of government school children in India

Nandivada et al. | Dec 11, 2022

Socio-economic and awareness correlates of physical activity of government school children in India

Here, based on the identified importance of physical activity in the development of young children, the authors investigated the effects of socioeconomic factors on the amount of physical activity of government-school children in India. They found significant differences between boys and girls, rural and urban, and children who were encouraged to exercise and those who were not. Overall, they suggest that their findings point to the important role of schools and communities in promoting healthy active lifestyles for developing children.

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A Cloud-Enabled Communication Strategy for Wildfire Alerts

Vinaithirthan et al. | Jul 19, 2020

A Cloud-Enabled Communication Strategy for Wildfire Alerts

The traditional alert system in California consists of Wireless Emergency Alerts (WEAs), which lack location specificity, and sign-up-based technology which is limited by the number of sign ups. Those who do not have phones or have a silence option on their devices are most at risk from the current alert system. Here the authors developed cloud-enabled crisis connection for disaster alerts (CRISIS-CONNECT) to mitigate problems associated with the current alert system.

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Developing a Portable, Reusable, and Inexpensive Magnesium-Air Fuel Cell

Tota et al. | Mar 28, 2019

Developing a Portable, Reusable, and Inexpensive Magnesium-Air Fuel Cell

One of the greatest challenges we face today is the sustainable production, storage, and distribution of electrical power. One emerging technology with great promise in this area is that of metal-air fuel cells—a long-term and reusable electricity storage system made from a reactive metal anode and a saline solution. In this study the authors tested several different types of metal to determine which was the most suitable for this application. They found that a fuel cell with a magnesium anode was superior to fuel cells made from aluminum or zinc, producing a voltage and current sufficient for real-world applications such as charging a mobile phone.

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Impact of daf-25 and daf-11 Mutations on Olfactory Function in C. elegans

Gardner et al. | Feb 02, 2019

Impact of daf-25 and daf-11 Mutations on Olfactory Function in C. elegans

Cilia are little hair-like protrusions on many cells in the human body, including those lining the trachea where they play a role in clearing our respiratory tract of mucous and other irritants. Genetic mutations that impair ciliary function have serious consequences on our well-being making it important to understand how ciliary function is regulated. By using a simple organism, such as the worm C. elegans that use cilia to move, the authors explore the effect of certain genetic mutations on the cilia of the worms by measuring their ability to move towards or away from certain odorants.

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