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Semantic segmentation - labelling each pixel in an image to a specific class- models require large amounts of manually labeled and collected data to train.

Irrespective of the final application of a molecule, synthetic accessibility is the rate-determining step in discovering and developing novel entities. However, synthetic complexity is challenging to quantify as a single metric, since it is a composite of several measurable metrics, some of which include cost, safety, and availability. Moreover, defining a single synthetic accessibility metric for both natural products and non-natural products poses yet another challenge given the structural distinctions between these two classes of compounds. Here, we propose a model for synthetic accessibility of all chemical compounds, inspired by the Central Limit Theorem, and devise a novel synthetic accessibility metric assessing the overall feasibility of making chemical compounds that has been fitted to a Gaussian distribution.

Metal-organic frameworks (MOFs) are promising new nanomaterials for use in the fight against climate change that can efficiently capture and convert CO₂ to other useful carbon products. This research used computational models to determine the reaction conditions under which MOFs can more efficiently capture and convert CO₂. In a cost-efficient manner, this analysis tested the hypothesis that pressure and temperature affect the efficacy of carbon capture and conversion, and contribute to understanding the optimal conditions for MOF performance to improve the use of MOFs for controlling greenhouse CO₂ emissions.

In this study, the authors use existing mathematical models to how high school athletes pace 800 m, 1600 m, and 3200 m distance track events compared to elite athletes.

In this study, the authors developed a model named DNA Sequence Embedding Network (DNA-SEnet) to classify DNA-asthma associations using their genomic patterns.

Using facial recognition as a use-case scenario, we attempt to identify sources of bias in a model developed using transfer learning. To achieve this task, we developed a model based on a pre-trained facial recognition model, and scrutinized the accuracy of the model’s image classification against factors such as age, gender, and race to observe whether or not the model performed better on some demographic groups than others. By identifying the bias and finding potential sources of bias, his work contributes a unique technical perspective from the view of a small scale developer to emerging discussions of accountability and transparency in AI.

The authors use MoralBERT, a BERT-based machine learning model, to analyze the prevalence and evolution of moral language in art critique journals from 1960 to 2015. They draw on Moral Foundations Theory to examine changes in five virtue and five vice foundations over time. They discover slight increases in degradation and care and a decrease in purity among otherwise stable patterns. The study is a novel application of computational moral analysis in a domain not typically associated with such tools. Although the moral signals were relatively faint, the study offers insights into shifting art world discourses and models an exciting method for future inquiry.

This study investigates how caffeine and melatonin affect learning in adolescent zebrafish, serving as a model for human teens. Using an automated system to track behavior, we found that melatonin slowed learning while caffeine caused erratic, inconsistent responses, suggesting both substances can negatively impact adolescent learning patterns. These findings highlight the need for further research into their physiological effects and potential implications for human adolescents.

The authors looked at how pharmacokinetics changed depending on the use of an in vitro or an in vivo model.

The authors looked at the impact of different harvest and feeding treatments on Heterandria formosa over three generations as a model for changes in marine ecosystems.