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Ramifications of natural and artificial sweeteners on the gastrointestinal system

Cowen et al. | Jun 19, 2023

Ramifications of natural and artificial sweeteners on the gastrointestinal system

This study aimed to determine whether artificial sweeteners are harmful to the human microbiome by investigating two different bacteria found to be advantageous to the human gut, Escherichia coli and Bacillus coagulans. Results showed dramatic reduction in bacterial growth for agar plates containing two artificial sweeteners in comparison to two natural sweeteners. This led to the conclusion that both artificial sweeteners inhibit the growth of the two bacteria and warrants further study to determine if zero-sugar sweeteners may be worse for the human gut than natural sugar itself.

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Recognition of animal body parts via supervised learning

Kreiman et al. | Oct 28, 2023

Recognition of animal body parts via supervised learning
Image credit: Kreiman et al. 2023

The application of machine learning techniques has facilitated the automatic annotation of behavior in video sequences, offering a promising approach for ethological studies by reducing the manual effort required for annotating each video frame. Nevertheless, before solely relying on machine-generated annotations, it is essential to evaluate the accuracy of these annotations to ensure their reliability and applicability. While it is conventionally accepted that there cannot be a perfect annotation, the degree of error associated with machine-generated annotations should be commensurate with the error between different human annotators. We hypothesized that machine learning supervised with adequate human annotations would be able to accurately predict body parts from video sequences. Here, we conducted a comparative analysis of the quality of annotations generated by humans and machines for the body parts of sheep during treadmill walking. For human annotation, two annotators manually labeled six body parts of sheep in 300 frames. To generate machine annotations, we employed the state-of-the-art pose-estimating library, DeepLabCut, which was trained using the frames annotated by human annotators. As expected, the human annotations demonstrated high consistency between annotators. Notably, the machine learning algorithm also generated accurate predictions, with errors comparable to those between humans. We also observed that abnormal annotations with a high error could be revised by introducing Kalman Filtering, which interpolates the trajectory of body parts over the time series, enhancing robustness. Our results suggest that conventional transfer learning methods can generate behavior annotations as accurate as those made by humans, presenting great potential for further research.

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Using machine learning to develop a global coral bleaching predictor

Madireddy et al. | Feb 21, 2023

Using machine learning to develop a global coral bleaching predictor
Image credit: Madireddy, Bosch, and McCalla

Coral bleaching is a fatal process that reduces coral diversity, leads to habitat loss for marine organisms, and is a symptom of climate change. This process occurs when corals expel their symbiotic dinoflagellates, algae that photosynthesize within coral tissue providing corals with glucose. Restoration efforts have attempted to repair damaged reefs; however, there are over 360,000 square miles of coral reefs worldwide, making it challenging to target conservation efforts. Thus, predicting the likelihood of bleaching in a certain region would make it easier to allocate resources for conservation efforts. We developed a machine learning model to predict global locations at risk for coral bleaching. Data obtained from the Biological and Chemical Oceanography Data Management Office consisted of various coral bleaching events and the parameters under which the bleaching occurred. Sea surface temperature, sea surface temperature anomalies, longitude, latitude, and coral depth below the surface were the features found to be most correlated to coral bleaching. Thirty-nine machine learning models were tested to determine which one most accurately used the parameters of interest to predict the percentage of corals that would be bleached. A random forest regressor model with an R-squared value of 0.25 and a root mean squared error value of 7.91 was determined to be the best model for predicting coral bleaching. In the end, the random model had a 96% accuracy in predicting the percentage of corals that would be bleached. This prediction system can make it easier for researchers and conservationists to identify coral bleaching hotspots and properly allocate resources to prevent or mitigate bleaching events.

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How planarians are affected by mouthwash and cough syrup

Mebane et al. | Nov 14, 2021

How planarians are affected by mouthwash and cough syrup

Since cough syrup and mouthwash are commonly used items and often end up flushed down the drain or toilet, they can eventually find their way into into freshwater waterways which can be harmful to many marine organisms, such as planarians (aquatic flatworms). To investigate the effects of these substances on planarians, the authors considered different concentrations of Listerine mouthwash and Robitussin syrup along with their active ingredients. By using a behavioral assay, they identified that the active ingredients of cough syrup detrimentally affect planarian behavior. They suggest that these findings could be used to guide disposal methods to lessen detrimental effects on aquatic life.

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A comparative analysis of machine learning approaches for prediction of breast cancer

Nag et al. | May 11, 2021

A comparative analysis of machine learning approaches for prediction of breast cancer

Machine learning and deep learning techniques can be used to predict the early onset of breast cancer. The main objective of this analysis was to determine whether machine learning algorithms can be used to predict the onset of breast cancer with more than 90% accuracy. Based on research with supervised machine learning algorithms, Gaussian Naïve Bayes, K Nearest Algorithm, Random Forest, and Logistic Regression were considered because they offer a wide variety of classification methods and also provide high accuracy and performance. We hypothesized that all these algorithms would provide accurate results, and Random Forest and Logistic Regression would provide better accuracy and performance than Naïve Bayes and K Nearest Neighbor.

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