Here, the authors investigated if dietary Omega-3 fatty acids could reduce the potential for cerebral cavernous malformations, which are brain lesions that occur due to a genetic mutation where high membrane permeability occurs between endothelial cell junctions. In a bovine-based study where some cows were fed an Omega-3 diet, the authors found the membranes of bovine blood cells increased in thickness with Omega-3 supplementation. As a result, they suggest that dietary Omega-3 could be considered as a possible preventative measure for cerebral cavernous malformations.

In this study, the authors tested whether the compound bromelain extracted from pineapples could protect skin cells from UV damage.

Sesame (Sesamum indicum) and moringa (Moringa oleifera) have natural antioxidants that could prevent cancer growth. Previously, this group found that sesame and moringa individually suppress eye tumor grown in the Drosophila melanogaster model. In the present study, combinations of sesame and moringa at different concentrations were included in the D. melanogaster diet. The impact on eye tumor development was assessed at different stages of growth.

Parkinson's disease is a neurodegenerative disorder that affects over 10 million people worldwide. It is caused by destruction of dopamine-producing neurons, which results in severe motor and movement symptoms. In this study, the authors investigated the anti-Parkinsonian effects of two natural compounds curcumin and nicotinamide using C. elegans as a model organism.

The authors test the antiproliferative and apoptosis-inducing properties of an extract created from a traditional Indian medicinal plant of the Amaranthus genus.

Here, based on the identification of androgapholide as a potential therapeutic treatment against cancer, Alzheimer's disease, diabetes, and multiple sclerosis, due to its ability to inhibit a signaling pathway in immune system function, the authors sought ways to optimize the natural product human systems by manipulating its chemical structure. Through the semisynthesis of a natural product along with computational studies, the authors developed an understanding of the kinetic mechanisms of andrographolide and semisynthetic analogs in the context of Michael additions.

The use of fertilizers is associated with an increase in soil degradation, which is predicted to lead to a decrease in crop production within the next decade. Thus, it is critical to find solutions to support crop production to sustain the robust global population. In this study, the authors investigate how probiotic bacteria, like Rhizobium leguminosarum, Bacillus subtilis and Pseudomonas fluorescens, can impact the growth of Arabidopsis thaliana when applied to the seeds.They hypothesized that solutions with multiple bacterial species compared to those with only a single bacterial species would promote seed germination more effectively.

Here, seeking to address the growing threat of multidrug-resistant bacteria (MDR). the authors used in silico virtual screening to target MDR Pseudomonas aeruginosa. They considered a key protein in its biosynthesis and virtually screened 20,000 candidates and 30 derivatives of brequinar. In the end, they identified a possible candidate with the highest degree of potential to inhibit the pathogen's lipid A synthesis.

In this study, the authors investigate the anti-cancer effects of Annona Reticulata (Ramphal or custard apple) by testing whether its extract could inhibit HeLa cell viability.

Patel et al. explore whether T. paniculatum plant extract can work with modern antibiotics to increase antibiotic efficacy against common disease-causing bacteria. The plant extract in conjunction with the antibiotic shows promise in battling S. aureus. The authors present a cost-effective method to increase antibiotic efficacy in a time where antibiotic resistant bacteria is becoming a growing problem.