In this article the authors look at the lung microbiome in patients with cystic fibrosis to determine what the major bacterial species present are.
Read More...Analysis of the lung microbiome in cystic fibrosis patients using 16S sequencing
In this article the authors look at the lung microbiome in patients with cystic fibrosis to determine what the major bacterial species present are.
Read More...Design and in silico screening of analogs of rilpivirine as novel non-nucleoside reverse transcriptase inhibitors (NNRTIs) for antiretroviral therapy
In this study, the authors use high-throughput virtual screening to design and evaluate a set of non-nucleoside reverse transcriptase inhibitors for binding affinity to the protein reverse transcriptase. These studies have important applications toward HIV therapies.
Read More...The Cilium- and Centrosome-Associated Protein CCDC11 Is Required for Cytokinesis via Midbody Recruitment of the ESCRT- III Membrane Scission Complex Subunit CHMP2A
In order for cells to successfully multiply, a number of proteins are needed to correctly coordinate the replication and division process. In this study, students use fluorescence microscopy and molecular methods to study CCDC11, a protein critical in the formation of cilia. Interestingly, they uncover a new role for CCDC11, critical in the cell division across multiple human cell lines.
Read More...The Impacts of Varying Types of Light on the Growth of Five Arabidopsis Varieties
Arabadopsis, “the fruit fly of plants”, is an easy to grow plant system for genetic manipulation. Here, researchers tested the effects of varied light conditions on plants with specific mutations in the light sensing pathways.
Read More...Blockchain databases: Encrypted for efficient and secure NoSQL key-store
Although commonly associated with cryptocurrency, blockchains offer security that other databases could benefit from. These student authors tested a blockchain database framework, and by tracking runtime of four independent variables, they prove this framework is feasible for application.
Read More...Heavy metal and bacterial water filtration using Moringa oleifera and coconut shell-activated carbon
One-third of the world's people do not have access to clean drinking water. Nadella and Nadella tackle this issue by testing a low-cost filtration system for removing heavy metal and bacteria from water.
Read More...Understanding the movement of professional and high school soccer players
In this article, the authors use datasets of professional and youth soccer players' movements to map and statistically compare them. Analysis compared movements that led to goals or no-goals and differences between pros and youth.
Read More...Evaluating Biomarkers and Treatments for Acute Kidney Injury in a Zebrafish Model
Coronary Artery Disease (CAD) is the leading cause of death in the United States, and 81% of Acute Kidney Injury (AKI) patients in the renal fibrosis stage later develop CAD. In this study, Mathew and Joykutty aimed to create a cost-effective strategy to treat AKI and thus prevent CAD using a model of the zebrafish, Danio rerio. They first tested whether AKI is induced in Danio rerio upon exposure to environmental toxins, then evaluated nitrotyrosine as an early biomarker for toxin-induced AKI. Finally, they evaluated 4 treatments of renal fibrosis, the last stage of AKI, and found that the compound SB431542 was the most effective treatment (reduced fibrosis by 99.97%). Their approach to treating AKI patients, and potentially prevent CAD, is economically feasible for translation into the clinic in both developing and developed countries.
Read More...Comparing model-centric and data-centric approaches to determine the efficiency of data-centric AI
In this study, three models are used to test the hypothesis that data-centric artificial intelligence (AI) will improve the performance of machine learning.
Read More...The Analysis of the Effects of Smoke and Water Vapor on Insect Pheromone Communication and Physical Condition: An Investigation of the Causes of Colony Collapse Disorder
The cause of insect colony collapse disorder (CCD) is still a mystery. In this study, the authors aimed to test the effects of two environmental factors, water vapor and smoke levels, on the social behavior and physical condition of insects. Their findings could help shed light on how changing environmental factors can contribute to CCD.
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