In this study the authors looked at the extract of Stephania tetrandra and its impact on symptoms related to obsessive compulsive disorder in fruit flies.
Read More...Administration of Stephania tetrandra to Drosophila melanogaster to create obsessive compulsive disorder model
In this study the authors looked at the extract of Stephania tetrandra and its impact on symptoms related to obsessive compulsive disorder in fruit flies.
Read More...Functional Network Connectivity: Possible Biomarker for Autism Spectrum Disorders (ASD)
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder and is difficult to diagnose in young children. Here magnetoencephalography was used to compare the brain activity in patients with ASD to patients in a control group. The results show that patients with ASD have a high level of activity in different areas of the brain than those in the control group.
Read More...Culturally Adapted Assessment Tool for Autism Spectrum Disorder and its Clinical Significance
Diagnosing of Autism Spectrum Disorder (ASD) using tools developed in the West is challenging in the Indian setting due to a huge diversity in sociocultural and economic backgrounds. Here, the authors developed a home-based, audiovisual game app (Autest) suitable for ASD risk assessment in Indian children under 10 years of age. Ratings suggested that the tool is effective and can reduce social inhibition and facilitate assessment. Further usage and development of Autest can improve risk assessment and early intervention measures for children with ASD in India.
Read More...Genetic underpinnings of the sex bias in autism spectrum disorder
Here, seeking to identify a possible explanation for the more frequent diagnosis of autism spectrum disorder (ASD) in males than females, they sought to investigate a potential sex bias in the expression of ASD-associated genes. Based on their analysis, they identified 17 ASD-associated candidate genes that showed stronger collective sex-dependent expression.
Read More...Post-Traumatic Stress Disorder (PTSD) biomarker identification using a deep learning model
In this study, a deep learning model is used to classify post-traumatic stress disorder patients through novel markers to assist in finding candidate biomarkers for the disorder.
Read More...Upregulation of the Ribosomal Pathway as a Potential Blood-Based Genetic Biomarker for Comorbid Major Depressive Disorder (MDD) and PTSD
Major Depressive Disorder (MDD), and Post-Traumatic Stress Disorder (PTSD) are two of the fastest growing comorbid diseases in the world. Using publicly available datasets from the National Institute for Biotechnology Information (NCBI), Ravi and Lee conducted a differential gene expression analysis using 184 blood samples from either control individuals or individuals with comorbid MDD and PTSD. As a result, the authors identified 253 highly differentially-expressed genes, with enrichment for proteins in the gene ontology group 'Ribosomal Pathway'. These genes may be used as blood-based biomarkers for susceptibility to MDD or PTSD, and to tailor treatments within a personalized medicine regime.
Read More...Analyzing the Relationships Between Internet Usage, Social Skill, and Anxiety Severity in Adults with Autism Spectrum Disorder
Here the authors investigate the use of social media in adults with Autism Spectrum Disorder (ASD) in affecting their ability and opportunities to interact with others. They found that higher usage of Internet correlated with less severe anxiety symptoms and improved social skills.
Read More...The precision of machine learning models at classifying autism spectrum disorder in adults
Autism spectrum disorder (ASD) is hard to correctly diagnose due to the very subjective nature of diagnosing it: behavior analysis. Due to this issue, we sought to find a machine learning-based method that diagnoses ASD without behavior analysis or helps reduce misdiagnosis.
Read More...The Analysis of the Effects of Smoke and Water Vapor on Insect Pheromone Communication and Physical Condition: An Investigation of the Causes of Colony Collapse Disorder
The cause of insect colony collapse disorder (CCD) is still a mystery. In this study, the authors aimed to test the effects of two environmental factors, water vapor and smoke levels, on the social behavior and physical condition of insects. Their findings could help shed light on how changing environmental factors can contribute to CCD.
Read More...The Perks of Watching a Movie: How the Portrayal of Anxiety and Depression in Film Affects Teenagers’ Perception of Anxiety and Depressive Disorders
In film, anxiety and depressive disorders are often depicted inaccurately. When viewers are exposed to these inaccurate portrayals, they collect misinformation about the disorders, as well as people who live with them, leading to stigma. This study used a mixed-method descriptive approach to analyze 16 teenagers’ attitudes towards people with anxiety and depression. Results found that while participants understood how these portrayals create stigma, they did not attribute this to misinformation. These results can be used to help both the film industry and the movie-going public better understand the effects of inaccurate storytelling and the extent to which it informs public perception
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