Current drug discovery processes can cost billions of dollars and usually take five to ten years. People have been researching and implementing various computational approaches to search for molecules and compounds from the chemical space, which can be on the order of 1060 molecules. One solution involves deep generative models, which are artificial intelligence models that learn from nonlinear data by modeling the probability distribution of chemical structures and creating similar data points from the trends it identifies. Aiming for faster runtime and greater robustness when analyzing high-dimensional data, we designed and implemented a Hybrid Quantum-Classical Generative Adversarial Network (QGAN) to synthesize molecules.
Insulin infusion patches are a common way for diabetics to receive medication. The durability of two different patch adhesives was compared on artificial skin with and without artificial sweat.
The authors here investigate the absorbency of two leading brands of diapers. They find that Huggies Little Snugglers absorb over 50% more salt water than Pampers Swaddlers, although both absorb significantly more fluid than what an average newborn can produce.
Understanding the techniques used to improve the adhesion strength of the epoxy resin is important especially for consumer applications such as repairing car parts, bonding aluminum sheeting, and repairing furniture or applications within the aviation or civil industry. Selleys Araldite epoxy makes specific strength claims emphasizing that the load or weight that can be supported by the adhesive is 72 kg/cm2. Nguyen and Clarke aimed to test the strength claims of Selley’s Araldite Epoxy by gluing two steel adhesion surfaces: a steel tube and bracket. Results showed that there is a lack of consideration by Selleys for adhesion loss mechanisms and environmental factors when accounting for consumer use of the product leading to disputable claims.
Here, recognizing the effects of the COVID-19 pandemic on young peoples' mental health and wellbeing the authors used an online survey which included the short General Health Questionnaire (GHQ-12) to probe 102 young adults. Overall they found that young adults perceived the pandemic to be detrimental to many areas of their wellbeing, with females and those aged 18-19 and 22-23 reporting to be the most significantly impacted.
The objective of this experiment is to determine if the medication albuterol has a positive impact on the lifespan of C. elegans. We hypothesize that if albuterol is added to the diet of C. elegans, then the lifespan of C. elegans will increase. Albuterol increased the mean lifespan of C. elegans by 4.31 ± 0.13 days, compared to the control group and increased the outer range of the C. elegans lifespan. The method of which this occurred is still unknown.
This study used hand-collected Greenhouse gas (GHG) emissions data from the Environmental Protection Agency (EPA) and aimed to understand the determinants and incentives of GHG emissions reduction. It explored how companies’ financials, Chief Executive Officer (CEO) compensation, and corporate governance affected GHG emissions. Results showed that companies reporting GHG emissions were wide-spread among the 48 industries represented by two-digit Standard Industrial Classification (SIC) codes.
Air pollution has detrimental effects on both the environment and humans. Here, researchers use graphene oxide to filter particulate matter from the air. Graphene oxide filters performed better than commercially available filters, effectively removing particulate matter from the air.