Here, recognizing the potential harmful effects of algal blooms, the authors used satellite images to detect algal blooms in water bodies in Wyoming based on their reflectance of near infrared light. They found that remote monitoring in this way may provide a useful tool in providing early warning and advisories to people who may live in close proximity.
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The effect of the consumption of the probiotic B. infantis on ethanol withdrawal symptoms in planaria (Dugesia dorotocephala)
Alcohol use disorder is a chronic, relapsing disease that affects millions of Americans every day. There are limited treatment options for alcohol dependence and alcohol withdrawal symptoms, including depression and anxiety. Previous studies have shown that probiotics can decrease depression in rodents during maternal separation and anxiety in humans. Therefore, we hypothesized that the ethanol-withdrawn planaria who consumed probiotics would have decreased withdrawal symptoms as measured by increased motility compared to the ethanol-withdrawn planaria that were not fed probiotics. The ethanol-withdrawn planaria had a statistically significant decrease in motility compared to the control group, while the planaria that consumed probiotics had no statistically significant change in motility compared to the control group.
Read More...Effect of hypervitaminosis A in regenerating planaria: A potential model for teratogenicity testing
This unique research study evaluated the potential use of the flatworm, brown planaria (Dugesia tigrine), as an alternative model for teratogenicity testing. In this study, we exposed amputated planaria to varying concentrations of a known teratogen, vitamin A (retinol), for approximately 2 weeks, and evaluated multiple parameters including the formation of blastema and eyes. The results from this study demonstrated that high concentrations of retinol caused defects in head and eye formation in regenerating planaria, with similarities to vitamin A related teratogenicity findings in mammals. Based on these results, regenerating brown planaria are a promising alternative model for teratogenicity testing, which can potentially be paradigm shifting as it can reduce cost, time, and pregnant animal use in research.
Read More...Impact of Population Density and Elevation on Tuberculosis Spread and Transmission in Maharashtra, India
India accounts for over 2.4 million recorded cases of tuberculosis, about 26% of the world’s cases. This research ascertained the bearing of both the population density and the average elevation above mean sea level (MSL) on the number of cases of TB recorded by the districts in Maharashtra, India. The results found a strong positive correlation between the number of TB cases per thousand people and the population density and a strong negative correlation between the number of TB cases per thousand people and the average elevation above MSL.
Read More...Pancreatic Adenocarcinoma: An Analysis of Drug Therapy Options through Interaction Maps and Graph Theory
Cancer is often caused by improper function of a few proteins, and sometimes it takes only a few proteins to malfunction to cause drastic changes in cells. Here the authors look at the genes that were mutated in patients with a type of pancreatic cancer to identify proteins that are important in causing cancer. They also determined which proteins currently lack effective treatment, and suggest that certain proteins (named KRAS, CDKN2A, and RBBP8) are the most important candidates for developing drugs to treat pancreatic cancer.
Read More...Utilizing 25-Hydroxyvitamin D3 to prevent the appearance of diabetic-like phenotypes in Drosophila melanogaster
This study aimed to assess the role of 25-hydroxyvitamin D3 solution, at varying concentrations, in protecting vertical transmission of diabetic-like phenotypes. We hypothesized that the highest concentration of vitamin D solution (55 ng/mL) would be most effective in having a protective role. The results indicated that the hypothesis was partially supported; overall, all three concentrations of the vitamin D solution administered to the flies reared on HSDs had a protective effect, to varying extents.
Read More...Slowing the Mold Growth on Stored Corn: The Effects of Vinegar, Baker’s Yeast, and Yogurt on Corn Weight Loss
Chemical preservatives are often used to reduce grain spoilage due to mold, but can have harmful heath and environmental effects. In this study, the authors tested three low toxic compounds for their effects on mold growth on corn kernels and found that all three were successful at slowing growth.
Read More...Using CRISPR technology to inhibit the replication of human cytomegalovirus by deletion of a gene promoter
Human cytomegalovirus (HCMV) causes serious infections in immunocompromised patients and therapies to inhibit latent HCMV are not developed. Using CRISPR/Cas9, the authors were able to delete an important promoter region in HCMV.
Read More...Simulations of Cheetah Roaming Demonstrate the Effect of Safety Corridors on Genetic Diversity and Human-Cheetah Conflict
Ecological corridors are geographic features designated to allow the movement of wildlife populations between habitats that have been fragmented by human landscapes. Corridors can be a pivotal aspect in wildlife conservation because they preserve a suitable habitat for isolated populations to live and intermingle. Here, two students simulate the effect of introducing a safety corridor for cheetahs, based on real tracking data on cheetahs in Namibia.
Read More...Qualitative tracking of human and animation motions reveals differences in their walking gaits
In their attempt to evoke a greater emotional connection with viewers, animators have strived to replicate human movements in their animations. However, animation movements still appear distinct from human movements. With a focus on walking, we hypothesized that animations, unaffected by real external forces (e.g. gravity), would move with a universally distinct, gliding gait that is discernible from humans.
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