Environment affects the progression of life, especially at the cellular level. This study investigates multiple 3-dimensional growth environments, also known as scaffolds or hydrogels, and their effect on the growth of a type of cells called fibroblasts. These results suggest that a scaffold made of collagen and polyethylene glycol are favorable for cell growth. This research is useful for developing implantable devices to aid wound healing.

In this report, Bhardwaj and Sharma tested whether placing specific plants indoors can reduce levels of indoor air pollution that can lead to lung-related illnesses. Using machine learning, they show that plants improved overall indoor air quality and reduced levels of particulate matter. They suggest that plant-based interventions coupled with sensors may be a useful long-term solution to reducing and maintaining indoor air pollution.

In this study, the authors investigate whether the addition of microbes from native soil enhanced the seed germination and growth of mung beans, pumpkins, and pea flower plants.

In this study, the authors study features of exoplanet 189733 b. This exoplanet, or planets that orbit stars other than the Sun, is found in the HD star system. Using a DSLR camera, they constructed a high caliber exoplanet transit detection tracker to study the orbital periods, radial velocity, and photometry of 189733 b. They then compared results from their system to data collected by other high precision studies. What they found was that their system produced results supporting previously published studies. These results are exciting results from the solar system demonstrating the importance of validating radial velocity and photometry data using high-precision studies.

Glioblastoma Multiforme (GBM) is the most malignant brain tumor with the highest fraction of genome alterations (FGA), manifesting poor disease-free status (DFS) and overall survival (OS). We explored The Cancer Genome Atlas (TCGA) and cBioportal public dataset- Firehose legacy GBM to study DNA repair genes Activating Signal Cointegrator 1 Complex Subunit 3 (ASCC3) and Alpha-Ketoglutarate-Dependent Dioxygenase AlkB Homolog 3 (ALKBH3). To test our hypothesis that these genes have correlations with FGA and can better determine prognosis and survival, we sorted the dataset to arrive at 254 patients. Analyzing using RStudio, both ASCC3 and ALKBH3 demonstrated hypomethylation in 82.3% and 61.8% of patients, respectively. Interestingly, low mRNA expression was observed in both these genes. We further conducted correlation tests between both methylation and mRNA expression of these genes with FGA. ASCC3 was found to be negatively correlated, while ALKBH3 was found to be positively correlated, potentially indicating contrasting dysregulation of these two genes. Prognostic analysis showed the following: ASCC3 hypomethylation is significant with DFS and high ASCC3 mRNA expression to be significant with OS, demonstrating ASCC3’s potential as disease prediction marker.

The authors propose a method to recycle Christmas tree needles into a non-toxic reducing agent for synthesizing copper nanoparticles.

Here, through protein-ligand docking, the authors investigated the effect of the interaction of emodin with serine/threonine kinases, a subclass of kinases that is overexpressed in many cancers, which is implicated in phosphorylation cascades. Through molecular dynamics theyfound that emodin forms favorable interactions with chitosan and chitosan PEG (polyethylene glycol) copolymers, which could aid in loading drugs into nanoparticles (NPs) for targeted delivery to cancerous tissue. Both polymers demonstrated reasonable entrapment efficiencies, which encourages experimental exploration of emodin through targeted drug delivery vehicles and their anticancer activity.

In this article, the authors investigate the shear modulus of different types of paper in the setting of the crumpling effect.

Diabetes is a growing health concern in the developing world. This study aimed to develop a questionnaire that uses factors including age, blood pressure, BMI, and family history to predict whether Filipino participants are at risk for diabetes.

The burning of fossil fuels, leading to an increased amount of carbon emissions, is the main cause of acid rain. Acid rain affects the process of photosynthesis, which makes the topic valuable to investigate. Our group utilizes plants to further investigate the relationship between pH value and photosynthesis. In this experiment, our group hypothesized that rain with a lower pH will decrease the rate of photosynthesis, causing less oxygen to be produced in the reaction.