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Influence of Infill Parameters on the Tensile Mechanical Properties of 3D Printed Parts

Guan et al. | Jul 17, 2020

Influence of Infill Parameters on the Tensile Mechanical Properties of 3D Printed Parts

Manufacturers that produce products using fused filament fabrication (FFF) 3D printing technologies have control of numerous build parameters. This includes the number of solid layers on the exterior of the product, the percentage of material filling the interior volume, and the many different types of infill patterns used to fill their interior.This study investigates the hypothesis that as the density of the part increases, the mechanical properties will improve at the expense of build time and the amount of material required.

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Interleukin family (IL-2 and IL-1β) as predictive biomarkers in Indian cancer patients: A proof of concept study

Parthasarathy et al. | Apr 03, 2023

Interleukin family (IL-2 and IL-1β) as predictive biomarkers in Indian cancer patients: A proof of concept study
Image credit: National Cancer Institute

Here, recognizing that the immune response to cancer results in biomarkers that can be used to assess the immune status of cancer patients, the authors investigated the concentrations of key cytokines (TH1 and TH2 cytokines) in healthy controls and cancer patients. They identified significant changes in resting and activated cytokine profiles, suggesting that data of biomarkers such as these could serve as a starting point for further treatment with regard to a patient's specific immune profile.

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The Long-Term Effect of CBD Crystals and CBD Oil on Depressive-Associated Rat Behaviors

Yang et al. | Dec 18, 2020

The Long-Term Effect of CBD Crystals and CBD Oil on Depressive-Associated Rat Behaviors

Cannabidiol (CBD) is a chemical extracted from cannabis and shown by some studies to alleviate the symptoms of many mental disorders, especially major depressive disorder. The authors hypothesized that chronic treatments with purified CBD through oral administration would relieve depression-associated behaviors in normal healthy rats under adverse conditions. A statistical analysis of the experimental data suggested that long-term consumption of CBD could elicit depression associated symptoms in normal rats without depression. The results imply that people should consume CBD-containing products with extreme caution and highlight the need to carefully monitor the use of CBD in health care products.

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Conversion of Mesenchymal Stem Cells to Cancer-Associated Fibroblasts in a Tumor Microenvironment: An in vitro Study

Ramesh et al. | Feb 18, 2020

Conversion of Mesenchymal Stem Cells to Cancer-Associated Fibroblasts in a Tumor Microenvironment: An <em>in vitro</em> Study

Mesenchymal stem cells(MSCs) play a role in tumor formation by differentiating into cancer associated fibroblasts (CAFs) which enable metastasis of tumors. The process of conversion of MSCs into CAFs is not clear. In this study, authors tested the hypothesis that cancers cells secrete soluble factors that induce differentiation by culturing bone marrow mesenchymal stem cells in media conditioned by a breast cancer cell line.

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The influence of implicit social pressure on prosocial behavior of adolescents

Carroll et al. | Dec 13, 2021

The influence of implicit social pressure on prosocial behavior of adolescents

In this study the authors sought to understand the influence of implicit social pressure on prosocial behavior (voluntary acts that benefit someone else) in adolescents age 12–19. They considered how participants divided money between themselves and four teammate they did a school project with. Despite being shown examples of how to divide money (social pressure), their results showed that both boys and girls were unaffected by prosocial, neutral, and antisocial pressures.

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Testing Different Polymers and Boron Nitride Nanotube Properties in Fabrication of Ion-selective Membranes

Yi et al. | Sep 28, 2020

Testing Different Polymers and Boron Nitride Nanotube Properties in Fabrication of Ion-selective Membranes

One largely untapped source of clean energy is the use of osmotic gradients where freshwater and saltwater are mixed, for example at estuaries. To harness such energy, charge-selective membranes are needed to separate the anions and cations in saltwater, establishing an electric potential like a battery. The objective of this study was twofold: to investigate the creation of the polymer matrix and test the properties of boron nitride nanotubes, as both are essential in the creation of an ion-selective membrane. Out of three polymer samples tested in this study, the mixture known as Soltech 704 showed the best resistance to etching, as well as the highest UV cure rate.

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A Crossover Study Comparing the Effect of a Processed vs. Unprocessed Diet on the Spatial Learning Ability of Zebrafish

Banga et al. | Sep 18, 2022

A Crossover Study Comparing the Effect of a Processed vs. Unprocessed Diet on the Spatial Learning Ability of Zebrafish

The authors compared the short-term effects of processed versus unprocessed food on spatial learning and survival in zebrafish, given the large public concern regarding processed foods. By randomly assigning zebrafish to a diet of brine shrimp flakes (processed) or live brine shrimp (unprocessed), the authors show while there is no immediate effect on a fish's decision process between the two diets, there are significant correlations between improved learning and stress response with the unprocessed diet.

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