Browse Articles

Analysis of Monotherapy and Combination Therapy on Helicobacter felis

Custodio et al. | Apr 28, 2020

Analysis of Monotherapy and Combination Therapy on <em>Helicobacter felis</em>

Heliobacter felis causes gastritis which is accompanied by a range of unpleasant symptoms in small animals such as cats. In order to identify effective antibiotics for treating H. felis infections, the researchers investigate whether a combination of different antibiotics is more effective than the use of individual antibiotics alone. Of the antibiotics they selected, Streptomycin alone was better than any other single antibiotic or in combination. Their results have not yet been validated in live animals, but suggest that Streptomycin alone might be an effective treatment of H. felis-induced gastritis in cats.

Read More...

Testing the Effects of Resveratrol, Apigenin, and Glucosamine to Effectively Reduce Prostate Cancer Cell Proliferation, Migration Levels, and Increase Apoptosis

Yang et al. | Apr 16, 2020

Testing the Effects of Resveratrol, Apigenin, and Glucosamine to Effectively Reduce Prostate Cancer Cell Proliferation, Migration Levels, and Increase Apoptosis

The current five-year survival rate of metastasized prostate cancer is only 30% and occurs in every one in nine men. Researchers have shown that people with a type of dwarfism called Laron’s Syndrome are immune to cancer due to their low levels of insulin-like growth factor-1 (IGF-1). For this reason, experimentally modifying the level of IGF-1 could provide better insight into whether lowering the levels of IGF-1 in prostate cancer cell lines (e.g. PC-3) could be an effective treatment to reduce their rates of proliferation and migration and increase apoptosis. We selected three compounds, which researchers have shown decrease IGF-1 levels, to test and combine to determine which is the most promising.

Read More...

The Effect of Ultraviolet Radiation and the Antioxidant Curcumin on the Longevity, Fertility, and Physical Structure of Drosophila melanogaster: Can We Defend Our DNA?

Lateef et al. | May 18, 2019

The Effect of Ultraviolet Radiation and the Antioxidant Curcumin on the Longevity, Fertility, and Physical Structure of <em>Drosophila melanogaster</em>: Can We Defend Our DNA?

Ultraviolet (UV) radiation is known to alter DNA structure and impair cellular function in all living organisms. In this study, Lateef et al examine the effects of UV radiation to determine whether antioxidant-enriched nutrition can combat the potential deleterious effects of UV radiation on Drosophila melanogaster. They found that UVB (320nm) radiation caused a 59% decrease in the Drosophila lifespan and mutagenic effects on flies' physical appearance, but did not significantly affect fertility. Curcumin significantly prolonged lifespan and enhanced fertility for both UV- and non-UV-exposed flies. The research demonstrates the positive potential of natural antioxidants as weapons against radiation-induced diseases including cancer.

Read More...

Covalently Entrapping Catalase into Calcium Alginate Worm Pieces Using EDC Carbodiimide as a Crosslinker.

Suresh et al. | Mar 31, 2019

Covalently Entrapping Catalase into Calcium Alginate Worm Pieces Using EDC Carbodiimide as a Crosslinker.

Catalase is a biocatalyst used to break down toxic hydrogen peroxide into water and oxygen in industries such as cheese and textiles. Improving the efficiency of catalase would help us to make some industrial products, such as cheese, less expensively. The best way to maintain catalase’s conformation, and thus enhance its activity, is to immobilize it. The primary goal of this study was to find a new way of immobilizing catalase.

Read More...

The Effects of Antioxidants on the Climbing Abilities of Drosophila melanogaster Exposed to Dental Resin

Prashanth et al. | Jan 17, 2019

The Effects of Antioxidants on the Climbing Abilities of <em>Drosophila melanogaster</em> Exposed to Dental Resin

Dental resins can be a source of reactive oxygen species (ROS) which in unruly amounts can be toxic to cellular and overall health. In this report, the authors test whether the consumption of antioxidant rich foods like avocado and asparagus can protect against the effect of dental resin-derived ROS. However, rather than testing humans, they use fruit flies and their climbing abilities as an experimental readout.

Read More...

Reducing Crop Damage Caused by Folsomia candida by Providing an Alternate Food Source

Tamura et al. | May 28, 2018

Reducing Crop Damage Caused by Folsomia candida by Providing an Alternate Food Source

Tamura and Moché found that Folsomia candida, a common crop pest, prefers to consume yeast instead of lettuce seedlings. The authors confirmed that even with the availability of both lettuce seedlings and yeast in the same dish, Folsomia candida preferred to eat the yeast, thereby reducing the number of feeding injuries on the lettuce seedlings. The authors propose that using this preference for yeast may be a way to mitigate crop damage by this pest.

Read More...

The Cosmic Microwave Background: Galactic Foregrounds and Faraday Rotation

Connelly et al. | Nov 20, 2017

The Cosmic Microwave Background: Galactic Foregrounds and Faraday Rotation

The cosmic microwave background (CMB) is faint electromagnetic radiation left over from early stages in the formation of the universe. In order to analyze the CMB, scientists need to remove from electromagnetic data foreground radiation that contaminates CMB datasets. In this study, students utilize extensive updated datasets to analyze the correlation between CMB maps and Faraday RM and WMAP sky maps.

Read More...