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Effect of Gram-positive bacteria on antibiotic resistance in Gram-negative bacteria

Willem et al. | Mar 12, 2024

Effect of Gram-positive bacteria on antibiotic resistance in Gram-negative bacteria

Antibiotics are one of the most common treatments for bacterial infections, but the emergence of antibiotic resistance is a major threat to the control of infectious diseases. Many factors contribute to the development of antibiotic resistance. One is bacterial conjugation from Gram-positive to Gram-negative bacteria where there is a transfer of resistance genes from Gram-positive to Gram-negative bacteria that could increase antibiotic resistance in the latter. In light of these observations, we decided to test whether Gram-negative bacteria that came into contact with Gram-positive bacteria had a higher resistance to the antimicrobial properties of spices than Gram-negative bacteria that did not come into contact with Gram-positive bacteria.

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Utilizing meteorological data and machine learning to predict and reduce the spread of California wildfires

Bilwar et al. | Jan 15, 2024

Utilizing meteorological data and machine learning to predict and reduce the spread of California wildfires
Image credit: Pixabay

This study hypothesized that a machine learning model could accurately predict the severity of California wildfires and determine the most influential meteorological factors. It utilized a custom dataset with information from the World Weather Online API and a Kaggle dataset of wildfires in California from 2013-2020. The developed algorithms classified fires into seven categories with promising accuracy (around 55 percent). They found that higher temperatures, lower humidity, lower dew point, higher wind gusts, and higher wind speeds are the most significant contributors to the spread of a wildfire. This tool could vastly improve the efficiency and preparedness of firefighters as they deal with wildfires.

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Predicting baseball pitcher efficacy using physical pitch characteristics

Oberoi et al. | Jan 11, 2024

Predicting baseball pitcher efficacy using physical pitch characteristics
Image credit: Antoine Schibler

Here, the authors sought to develop a new metric to evaluate the efficacy of baseball pitchers using machine learning models. They found that the frequency of balls, was the most predictive feature for their walks/hits allowed per inning (WHIP) metric. While their machine learning models did not identify a defining trait, such as high velocity, spin rate, or types of pitches, they found that consistently pitching within the strike zone resulted in significantly lower WHIPs.

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Aberrant response to dexamethasone suppression test associated with inflammatory response in MDD patients

Ulery et al. | Nov 06, 2023

Aberrant response to dexamethasone suppression test associated with inflammatory response in MDD patients

Major depressive disorder (MDD) is a prevalent mood disorder. The direct causes and biological mechanisms of depression still elude understanding, though genetic factors have been implicated. This study looked to identify the mechanism behind the aberrant response to the dexamethasone suppression test (DST) displayed by MDD patients, in which they display a lack of cortisol suppression. Analysis revealed several pro-inflammatory genes that were significant and differentially expressed between affected and non-affected groups in response to the DST. Looking at ways to decrease the inflammatory response could have implications for treatment and may explain why some people treated for depression still display symptoms or may lead researchers to different classes of drugs for treatment.

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Collaboration beats heterogeneity: Improving federated learning-based waste classification

Chong et al. | Jul 18, 2023

Collaboration beats heterogeneity: Improving federated learning-based waste classification

Based on the success of deep learning, recent works have attempted to develop a waste classification model using deep neural networks. This work presents federated learning (FL) for a solution, as it allows participants to aid in training the model using their own data. Results showed that with less clients, having a higher participation ratio resulted in less accuracy degradation by the data heterogeneity.

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Suppress that algae: Mitigating the effects of harmful algal blooms through preemptive detection & suppression

Natarajan et al. | Jul 17, 2023

Suppress that algae: Mitigating the effects of harmful algal blooms through preemptive detection & suppression
Image credit: Sharanya Natarajan

A bottleneck in deleting algal blooms is that current data section is manual and is reactionary to an existing algal bloom. These authors made a custom-designed Seek and Destroy Algal Mitigation System (SDAMS) that detects harmful algal blooms at earlier time points with astonishing accuracy, and can instantaneously suppress the pre-bloom algal population.

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A comparison of use of the mobile electronic health record by medical providers based on clinical setting

Stover et al. | Jul 12, 2023

A comparison of use of the mobile electronic health record by medical providers based on clinical setting
Image credit: Tima Miroshnichenko

The electronic health record (EHR), along with its mobile application, has demonstrated the ability to improve the efficiency and accuracy of health care delivery. This study included data from 874 health care providers over a 12-month period regarding their usage of mobile phone (EPICĀ® Haiku) and tablet (EPICĀ® Canto) mEHR. Ambulatory and inpatient care providers had the greatest usage levels over the 12-month period. Awareness of workflow allows for optimization of mEHR design and implementation, which should increase mEHR adoption and usage, leading to better health outcomes for patients.

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