Alzheimer's disease is one of the leading causes of death in the United States and is characterized by neurodegeneration. Mishra et al. wanted to understand the role of two transport proteins, LRP1 and AQP4, in the neurodegeneration of Alzheimer's disease. They used a model organism for Alzheimer's disease, the nematode C. elegans, and genetic engineering to look at whether they would see a decrease in neurodegeneration if they increased the amount of these two transport proteins. They found that the best improvements were caused by increased expression of both transport proteins, with smaller improvements when just one of the proteins is overly expressed. Their work has important implications for how we understand neurodegeneration in Alzheimer's disease and what we can do to slow or prevent the progression of the disease.

The printing-related expenditure that is budgeted in 2014 for U.S. Federal agencies is $1.8 billion. A sample of five publically available documents produced by various federal agencies is analyzed and the cost savings arising from a change in font type are estimated. The analysis predicts that the Government’s annual savings by switching to Garamond are likely to be about $234 million with worst-case savings of $62 million and best-case savings of $394 million. Indirect benefits arising from a less detrimental impact on the environment due to lower ink production and disposal volumes are not included in these estimates. Times New Roman is not as efficient as Garamond, and the third federally-recommended font, Century Gothic, is actually worse on average than the fonts used in the sample documents.

In this study, the authors investigate the effect of remote learning (due to the COVID-19 pandemic) on sleeping habits amongst teenagers in Ohio. Using survey results, sleep habits and attitudes toward school were assessed before and after the COVID-19 pandemic.

In this study the authors looked at the ability of artificial intelligence to detect tempo, rhythm, and intonation of a piece played on violin. Technology such as this would allow for students to practice and get feedback without the need of a teacher.

In this study, the authors investigate the effects of different algal growth media on algae's ability to perform carbon dioxide biofixation, or utilize carbon dioxide by fixing it into fatty acids within the cells. More specifically, carbon dioxide biofixation of Chlorella vulgaris was cultured in one of four media options and carbon dioxide was measured and compared to controls. The study results demonstrated that the use of media can enhance algae's capacity for biofixation and this has important implications for developing methods to reduce carbon dioxide in the environment.

This study examined the relationship between the slope of a terrain and vegetation, measured by the normalized difference vegetation index (NDVI). It was hypothesized that lower slope ranges would be more supportive of vegetation growth than higher slope ranges. Analysis showed that no slope (even as extreme as 85–90°) prohibits the growth of vegetation completely; even the steepest slopes examined contain plant life. Knowing that steep slopes can still support plant life, agriculturalists can begin to explore and start planting additional crops and plants at these extreme slopes.

Each year, large amounts of carcinogenic pollutants are released into the environment, which negatively affects human health. This study ranks the major carcinogenic pollutants that are released into the air, water, and land by both the total released amounts and the potential carcinogenic risks.

In this study, we performed orthotopic auto-transplantation of fresh ovarian tissues by transplanting unilateral half ovarian tissue to the contralateral ovary in the ICR (Institute of Cancer Research) strain of outbred, heterogeneous mice to determine if the transplanted tissue could be functional. We found that the freshly transplanted mouse ovarian tissue survived and functional, as histochemical and immunofluorescence assays have shown that not only both follicles at different developing stages and corpus luteum are available, but the morphology of them are properly maintained within the transplanted tissue.

The authors investigated an important parasite-host relationship between the raccoon roundworm and the raccoon to understand how parasite prevalence is affected by location. They found that the parasite infection was more prevalent in raccoons found closer to human dwellings, though the number of roundworm eggs was not significantly different. These results are important human health, since roundworm infection is lethal to humans and can be transmitted from raccoons to humans - the authors suggest that more research into this parasite and awareness of its prevalence is needed to prevent disease.

This study examined the ability of copper and copper alloy surfaces to inhibit bacterial growth, which may be help prevent healthcare-associated infections. The authors exposed two non-pathogenic strains of bacteria to different metal plates for varying degrees of time and measured bacterial growth.