A central challenge of cancer therapy is identifying treatments that will effectively target cancer cells while minimizing effects on healthy cells. To identify potential targets for treating a multiple myeloma, a frequently incurable cancer, Kochenderfer and Kochenderfer analyze RNA sequencing data from the Cancer Cell Line Encyclopedia to find genes with high expression in multiple myeloma cells and low expression in normal tissues

The authors test the usefulness of zinc oxide microparticles relative to zinc oxide nanoparticles as antibacterial agents.

Natural selection shapes the evolution of all organisms, and one question of interest is whether natural selection will reach a "stopping point": a stable, ideal, value for any particular trait. Madhan and Kanagavel tackle this question by building a computer simulation of trait evolution in organisms.

The authors compare nutritional content of foods found in Western versus Asian grocery stores to determine whether one cultural diet is healthier than the other.

We know relatively little about how vegan diets and non-vegan diets compare when it comes to the gut microbiome. Gollamudi and Gollamudi tackle this challenge by investigating how changes in a participant's diet affected the diversity of their intestinal microbiome.

The energy of an atom is extremely useful in nuclear physics and reaction mechanism pathway determination but is challenging to compute. This work aimed to synthesize regression models for Pople Gaussian expansions of Slater-type Orbitals (STO-nG) atomic energy vs. atomic number scatter plots to allow for easy approximation of atomic energies without using computational chemistry methods. The data indicated that of the regressions, sinusoidal regressions most aptly modeled the scatter plots.

Cardiovascular diseases are the largest cause of death globally, making it a critical area of focus. The circulatory system is required to make the heart function. One component of this system is blood vessels, which is the focus of our study. Our work aims to demonstrate the numeric relationship between a blood vessel's diameter and the number of pumps needed to transport blood.

Here the authors sought to better understand glioma, cancer that occurs in the glial cells of the brain with gene expression profile analysis. They considered the expression of complement system genes across the transcriptional and IDH-mutational subtypes of low-grade glioma and glioblastoma. Based on their results of their differential gene expression analysis, they found that outcomes vary across different glioma subtypes, with evidence suggesting that categorization of the transcriptional subtypes could help inform treatment by providing an expectation for treatment responses.

While resources on the safety of household cleaning products are plentiful, measures of efficacy of these cleaning chemicals against bacteria and viruses remain without standardization in the consumer market. The COVID pandemic has exasperated this knowledge gap, stoking the growth of misinformation and misuse surrounding household cleaning chemicals. Arriving at a time dire for sanitization standardization, the authors of this paper have created a quantifying framework for consumers by comparing a wide range of household cleaning products in their efficacy against bacteria generated by a safe and easily replicable yogurt model.

Here, the authors sought to identify a method to optimize the lift generated by an airfoil based solely on its shape. By beginning with a Bernoullian model to predict an optimized wing shape, the authors then tested their model against other possible shapes by constructing them from Styrofoam and testing them in a small wind tunnel. Contrary to their hypothesis, they found their expected optimal airfoil shape did not result in the greatest lift generation. They attributed this to a variety of confounding variables and concluded that their results pointed to a correlation between airfoil shape and lift generation.