Bacterial infection is resurging as one of the most dangerous challenges facing the medical establishment. Americans spend about 55 to 70 billion dollars per year on antibiotics, yet these antibiotics are becoming increasingly ineffective as illness-causing bacteria gain resistance to the prescribed drugs. We tested if 11 commonly-used spices could inhibit growth of the gram-negative bacteria, E. coli, the main takeaway from these experiments is that certain spices and herbs have antibacterial effects that inhibit growth of E.coli , and these spices could show similarly promising activity towards other bacteria.

In this study, the authors developed and assessed the accuracy of a machine learning algorithm to identify skin cancers using images of biopsies.

The authors test the antiproliferative and apoptosis-inducing properties of an extract created from a traditional Indian medicinal plant of the Amaranthus genus.

In this study, the authors identify new potential targets to treat advanced diffuse large B-cell lymphoma after treatment relapse and loss of CD19 expression.

Malaria is a major public health issue, especially in developing countries, and vector control is a major facet of malaria eradication efforts. Recently, sterile insect technique (SIT), or the release of sterile mosquitoes into the wild, has shown significant promise as a method of keeping vector populations under control. In this study, the authors investigate the Anopheles gambiae transglutaminase 3 protein (AgT3), which is essential to the mating of the Anopheles mosquito. They show that an active site mutation is able to abolish the activity of the AgT3 enzyme and propose it as a potential target for chemosterilant inhibitors.

In this study the authors looked at the extract of Stephania tetrandra and its impact on symptoms related to obsessive compulsive disorder in fruit flies.

In this study, the authors studied the ability for bacteria to develop antibiotic resistance over successive generations and modeled the trajectory to predict how antibiotic resistance is developed.

In this study, the authors conduct a bibliometric analysis to understand the recent growth in and current state of peripheral nerve regeneration research. They also explored potential future studies.

Oligodendrocytes are specialized brain cells that can change to cells that produce myelin and protect nerves. This study investigates the capacity for different extracellular matrix cues to induce this effect in culture.

Human cytomegalovirus (HCMV) causes serious infections in immunocompromised patients and therapies to inhibit latent HCMV are not developed. Using CRISPR/Cas9, the authors were able to delete an important promoter region in HCMV.