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The juxtaposition of anatomy and physics in the eye

Zhou et al. | Oct 25, 2023

The juxtaposition of anatomy and physics in the eye

People are quick to accept the assumption that a light will appear dimmer the farther away they are, citing the inverse square relationship that illuminance obeys as rationale. However, repeated observations of light sources maintaining their brightness over large distances prompted us to explore how the brightness, or perceived illuminance of a light varies with the viewing distance from the object. We hypothesized that since both the illuminance of the light source and image size decrease at the same rate, then the concentration, or intensity of the image remains unchanged, and subsequently the perceived illuminance.

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Interleukin family (IL-2 and IL-1β) as predictive biomarkers in Indian cancer patients: A proof of concept study

Parthasarathy et al. | Apr 03, 2023

Interleukin family (IL-2 and IL-1β) as predictive biomarkers in Indian cancer patients: A proof of concept study
Image credit: National Cancer Institute

Here, recognizing that the immune response to cancer results in biomarkers that can be used to assess the immune status of cancer patients, the authors investigated the concentrations of key cytokines (TH1 and TH2 cytokines) in healthy controls and cancer patients. They identified significant changes in resting and activated cytokine profiles, suggesting that data of biomarkers such as these could serve as a starting point for further treatment with regard to a patient's specific immune profile.

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The Role of Corresponding Race, Gender, and Species as Incentives for Charitable Giving

Antonides-Jensen et al. | Jul 31, 2019

The Role of Corresponding Race, Gender, and Species as Incentives for Charitable Giving

Inherent bias is often the unconscious driver of human behavior, and the first step towards overcoming these biases is our awareness of them. In this article the authors investigate whether race, gender or species affect the choice of charity by middle class Spaniards. Their conclusions serve as a starting point for further studies that could help charities refine their campaigns in light of these biases effectively transcending them or taking advantage of them to improve their fundraising attempts.

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Inhibiting the ERK pathway and the TRPM7 ion channel in gastric and bladder cancer cells

Yang et al. | Oct 14, 2021

Inhibiting the ERK pathway and the TRPM7 ion channel in gastric and bladder cancer cells

In this work the authors investigate new possible treatment methods for gastric and bladder cancers. They specifically targeted the transient receptor potential cation subfamily M member 7 (TRPM7), an ion channel that plays an important role in the survival of both of these cancers, and extracellular regulated kinases (ERKs),which contributes to the carcinogenesis of many cancers including gastric cancer. As a result, the authors consider the effects of Ginsenoside Rd, NS8593, curcumin, and icariin , known to inhibit TRPM7 and ERK. The authors found that these treatments decrease proliferation and induce apoptosis in studies of gastric and bladder cancer cells.

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Failure of colony growth in probiotic Lactobacillus casei Shirota as result of preservative sorbic acid

Raymond et al. | May 07, 2023

Failure of colony growth in probiotic <i>Lactobacillus casei</i> Shirota as result of preservative sorbic acid

This study tested the proficiency of different concentrations of the antimicrobial sorbic acid to inhibit the probiotic Lactobacillus casei Shirota. It was hypothesized that sorbic acid’s use as a bacterial deterrent would also target this bacterial strain of Lactobacillus. The results supported the hypothesis, with the colony count of L. casei Shirota having significant decreases at all concentrations of sorbic acid. These results additionally suggest that even under the FDA sorbic acid restrictions of 0.03% concentration, damaging effects could be seen in L. casei Shirota.

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Albuterol extends lifespan of Caenorhabditis elegans

Belkin et al. | Oct 19, 2021

Albuterol extends lifespan of <i>Caenorhabditis elegans</i>

The objective of this experiment is to determine if the medication albuterol has a positive impact on the lifespan of C. elegans. We hypothesize that if albuterol is added to the diet of C. elegans, then the lifespan of C. elegans will increase. Albuterol increased the mean lifespan of C. elegans by 4.31 ± 0.13 days, compared to the control group and increased the outer range of the C. elegans lifespan. The method of which this occurred is still unknown.

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A comparative study on the suitability of virtual labs for school chemistry experiments

Praveen et al. | Aug 22, 2022

A comparative study on the suitability of virtual labs for school chemistry experiments

Virtual labs have been gaining popularity over the last few years, especially during the worldwide lockdown due to the COVID-19 pandemic. In this study, the suitability of virtual labs for school chemistry experiments is addressed and their effectiveness is compared to traditional physical lab experiments by focusing on physical and human resources, convenience, cost, safety, and time involved as well as topic "matter".

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