![Eggshell consumption in different reproductive stages and broods of the Western Bluebird, <em>Sialia mexicana</em>](/rails/active_storage/representations/proxy/eyJfcmFpbHMiOnsibWVzc2FnZSI6IkJBaHBBdEFKIiwiZXhwIjpudWxsLCJwdXIiOiJibG9iX2lkIn19--095d4ce24ed77baab2fd0f52ca5772564ab42514/eyJfcmFpbHMiOnsibWVzc2FnZSI6IkJBaDdCem9MWm05eWJXRjBTU0lJYW5CbkJqb0dSVlE2QzNKbGMybDZaVWtpRFRZd01IZzJNREErQmpzR1ZBPT0iLCJleHAiOm51bGwsInB1ciI6InZhcmlhdGlvbiJ9fQ==--a3b53ba1a0f83efef18f6e75a8d4ce784384bee2/caroline-attwood-K9pO8lHUelE-unsplash.jpg)
The authors investigate whether Western Bluebirds and other perching birds consume eggshells, as a source of calcium, at a greater rate before reproduction and during nest building when they are unable to store calcium.
Read More...Eggshell consumption in different reproductive stages and broods of the Western Bluebird, Sialia mexicana
The authors investigate whether Western Bluebirds and other perching birds consume eggshells, as a source of calcium, at a greater rate before reproduction and during nest building when they are unable to store calcium.
Read More...A chemical and overwintering honey bee apiary field study comparing new and expired amitraz miticide
In this study, the authors test the longevity of a anti-mite compound, amitraz, in commercially-sold strips and the age-dependent efficacy of these strips in preventing honey bee colony collapse by ectoparasitic mite Varroa destructor.
Read More...Collaboration beats heterogeneity: Improving federated learning-based waste classification
Based on the success of deep learning, recent works have attempted to develop a waste classification model using deep neural networks. This work presents federated learning (FL) for a solution, as it allows participants to aid in training the model using their own data. Results showed that with less clients, having a higher participation ratio resulted in less accuracy degradation by the data heterogeneity.
Read More...Substance Abuse Transmission-Impact of Parental Exposure to Nicotine/Alcohol on Regenerated Planaria Offspring
The global mental health crisis has led to increased substance abuse among youth. Prescription drug abuse causes approximately 115 American deaths daily. Understanding intergenerational transmission of substance abuse is complex due to lengthy human studies and socioeconomic variables. Recent FDA guidelines mandate abuse liability testing for neuro-active drugs but overlook intergenerational transfer. Brown planaria, due to their nervous system development similarities with mammals, offer a novel model.
Read More...The influence of purpose-of-use on information overload in online social networking
Here, seeking to understand the effects of social media in relation to social media fatigue and/or overload in recent years, the authors used various linear models to assess the results of a survey of 27 respondents. Their results showed that increased duration of use of social media did not necessarily lead to fatigue, suggesting that quality may be more important than quantity. They also considered the purpose of an individual's social media usage as well as their engagement behavior during the COVID-19 pandemic.
Read More...In vitro Comparison of Anticancer and Immunomodulatory Activities of Resveratrol and its Oligomers
Resveratrol is a type of stillbenoid, a phenolic compound produced in plants, that is known for its anti-inflammatory and anticancer effects. Many oligomers of resveratrol have recently been isolated their bioactivities remain unknown. Here, authors compared the bioactivities of resveratrol with natural dimers (ε-viniferin and gnetin H) and trimers (suffruticosol B and C). Results provide preliminary evidence that resveratrol oligomers could be potential preventive or therapeutic agents for cancers and other immune-related diseases
Read More...Wound healing properties of mesenchymal conditioned media: Analysis of PDGF, VEGF and IL-8 concentrations
Regenerative medicine has become a mainstay in recent times, and employing stem cells to treat several degenerative, inflammatory conditions has resulted in very promising outcomes. These forms of cell-based therapies are novel approaches to existing treatment modalities. In this study, the authors compared the concentrations of the cytokines PDGF, IL-8, and VEGF between conditioned and spent media of mesenchymal stem cells (MSCs) to evaluate their potential therapeutic properties for wound healing in inflammatory conditions. They hypothesized that conditioned media contains higher concentrations of wound healing cytokines compared to spent media. The authors found that while IL-8 and VEGF were present in highest concentrations in conditioned media, PDGF was present in maximal amounts in spent media.
Read More...The gender gap in STEM at top U.S. Universities: change over time and relationship with ranking
Authors address the gender disparity in STEM fields, examining changes in gender diversity across male-dominated undergraduate programs over 19 years at 24 top universities. Analyzing data from NCES IPEDS, it identifies STEM as persistently male-dominated but notes increasing gender diversity in many disciplines, particularly in recent years. Results indicate that higher-ranked universities in disciplines like computer science and mechanical engineering show a weak correlation with improved gender diversity, suggesting effective initiatives can mitigate the gender gap in STEM, despite ongoing challenges.
Read More...Unveiling the wound healing potential of umbilical cord derived conditioned medium: an in vitro study
Chronic wounds pose a serious threat to an individual’s health and quality of life. However, due to the severity and morbidity of such wounds, many pre-existing treatments are inefficient or costly. While the use of skin grafts and other such biological constructs in chronic wound healing has already been characterized, the use of umbilical cord tissue has only recently garnered interest, despite the cytokine-rich composition of Wharton’s jelly (cord component). Our current study aimed to characterize the use of an umbilical cord derived conditioned medium (UC-CM) to treat chronic wounds.
Read More...Effects of vascular normalizing agents on immune marker expression in T cells, dendritic cells, and melanoma cells
Tertiary lymphoid structures (TLS) are lymph node-like structures that form at sites of inflammation, and their presence in cancer patients is predictive of a better clinical outcome. One significant obstacle to TLS formation is reduced immune cell infiltration into the tumor microenvironment (TME). Recent studies have shown that vasculature normalizing (VN) agents may override this defect to improve tissue perfusion and increased immune cell entry into the TME. However, their effects on immune cell and tumor cell phenotype remain understudied. Here the authors investigate whether treating tumor cells with VN would reduce their immunosuppressive phenotype and promote production of chemokine that recruit immune cells and foster TLS formation.
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