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Employee resignation study in Fairfax County

Zhang et al. | Mar 03, 2023

Employee resignation study in Fairfax County

In this study, the authors address potential reasons why employees may voluntarily resign. This is in response to the currently observed economic trend The Great Resignation. Through analysis of federal and local government data along with survey results from Fairfax County, they concluded that adding additional benefits will help companies retain talented empolyees.

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Linearity of piezoelectric response of electrospun polymer-based (PVDF) fibers with barium titanate nanoparticles

Nichitiu et al. | Feb 13, 2023

Linearity of piezoelectric response of electrospun polymer-based (PVDF) fibers with barium titanate nanoparticles

Here, seeking to develop an understanding of the properties that determine the viability of piezoelectric flexible materials for applications in electro-mechanical sensors, the authors investigated the effects of the inclusion BaTiO3 nanoparticles in electrospun Polyvinyledene Fluoride. They found the voltage generated had a piecewise linear dependence on the applied force at a few temperatures.

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Autologous transplantation of fresh ovarian tissue in the ICR mice model

Wang et al. | Oct 24, 2022

Autologous transplantation of fresh ovarian tissue in the ICR mice model

In this study, we performed orthotopic auto-transplantation of fresh ovarian tissues by transplanting unilateral half ovarian tissue to the contralateral ovary in the ICR (Institute of Cancer Research) strain of outbred, heterogeneous mice to determine if the transplanted tissue could be functional. We found that the freshly transplanted mouse ovarian tissue survived and functional, as histochemical and immunofluorescence assays have shown that not only both follicles at different developing stages and corpus luteum are available, but the morphology of them are properly maintained within the transplanted tissue.

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Investigation of unknown causes of uveal melanoma uncovers seven recurrent genetic mutations

Nanda et al. | Aug 25, 2022

Investigation of unknown causes of uveal melanoma uncovers seven recurrent genetic mutations

Uveal melanoma (UM) is a rare subtype of melanoma but the most frequent primary cancer of the eye in adults. The goal of this study was to research the genetic causes of UM through a comprehensive frequency analysis of base-pair mismatches in patient genomes. Results showed a total of 130 genetic mutations, including seven recurrent mutations, with most mutations occurring in chromosomes 3 and X. Recurrent mutations varied from 8.7% to 17.39% occurrence in the UM patient sample, with all mutations identified as missense. These findings suggest that UM is a recessive heterogeneous disease with selective homozygous mutations. Notably, this study has potential wider significance because the seven genes targeted by recurrent mutations are also involved in other cancers.

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