Regenerative medicine has become a mainstay in recent times, and employing stem cells to treat several degenerative, inflammatory conditions has resulted in very promising outcomes. These forms of cell-based therapies are novel approaches to existing treatment modalities. In this study, the authors compared the concentrations of the cytokines PDGF, IL-8, and VEGF between conditioned and spent media of mesenchymal stem cells (MSCs) to evaluate their potential therapeutic properties for wound healing in inflammatory conditions. They hypothesized that conditioned media contains higher concentrations of wound healing cytokines compared to spent media. The authors found that while IL-8 and VEGF were present in highest concentrations in conditioned media, PDGF was present in maximal amounts in spent media.

FBS is an important component in in vitro cell culture work, helping to provide needed nutrients to cells to grow. The authors look at the ability of an alternative to FBS to support cell growth in culture.

In this study, the effects of different sources of serum on growing mesenchymal stem cells are compared with the goal of identifying one more suitable for clinical use.

Reducing paint drying time is an important step in improving production efficiency and reducing costs. The authors hypothesized that decreased humidity would lead to faster drying, ultraviolet (UV) light exposure would not affect the paint colors differently, white light exposure would allow for longer wavelength colors to dry at a faster rate than shorter wavelength colors, and substrates with higher roughness would dry slower. Experiments showed that trials under high humidity dried slightly faster than trials under low humidity, contrary to the hypothesis. Overall, the paint drying process is very much dependent on its surrounding environment, and optimizing the drying process requires a thorough understanding of the environmental factors and their interactive effects with the paint constituents.

The authors seek to accelerate wound healing by reducing inflammation with a cocktail containing growth factors and bioactive modulators.

Cardiac autonomic and structural changes may occur in temporal lobe epilepsy patients and contribute to the risk of sudden unexpected death in epilepsy patients. Choi and colleagues reviewed clinical charts to obtain patients’ lifetime seizure count, antiepileptic drug use, and history of heart disease, followed by transthoracic echocardiogram to calculate left ventricle dimensions, ejection fraction, and left ventricle mass. By comparing epilepsy patients to control subjects, they found that epilepsy patients had thinner left ventricle walls and smaller ejection fraction, but with no significant difference in left ventricle mass.

Invasive species pose a significant threat to many ecosystems, whether by outcompeting native species and disturbing food webs, or through increasing risks of natural disasters like flooding and wildfires. The ornamental grass species Pennisetum villosum R. Br. was previously identified by the California Invasive Plant Council as being potentially invasive; this experiment was conducted to determine if P. villosum displays characteristics of an invasive species when grown in a California chaparral environment. Reults found that in both conditions, the two species had similar germination rates, and that P. villosum grew significantly larger than N. pulchra for around 95 days.

With low-temperature transportation being critical for the progress of research and medical services by preserving biological samples and vaccines, the optimization of cold storage materials is more critical now than ever. The exclusive use of dry ice has its limitations. Notably, it proves insufficient for cold storage during long-range transportation necessary for the delivery of specimens to rural areas. In this article, the authors have proposed a new means of cold storage through the combination of dry ice and ethanol. Upon thorough analysis, the authors have determined their new method as considerably better than the use of pure dry ice across many characteristics, including cold storage capacity, longevity of material, and financial and environmental feasibility.

As levels of food waste continue to rise, it is essential to find improved techniques of prolonging the shelf life of produce. The authors aimed to find a simple, yet effective, method of slowing down spoilage in tomatoes. Linear regression analysis revealed that the tomatoes soaked salt water and not dried displayed the lowest correlation between time and spoilage, confirming that this preparation was the most effective.

Research relating to freshwater acidification is minimal, so the impact of aquatic plants, Anubias barteri var. congensis and Anubias barteri var. nana, on minimizing changes in pH was explored in an ecosystem in Northern California. Creek water samples, with and without the aquatic plants, were exposed to dry ice to simulate carbon emissions and the pH was monitored over an eight-hour period. There was a 25% difference in the observed pH based on molar hydrogen ion concentration between the water samples with plants and those without plants, suggesting that aquatic plants have the potential to limit acidification to some extent. These findings can guide future research to explore the viable partial solution of aquatic plants in combating freshwater acidification.