In this study, the authors identify transcripts and gene networks that are changed after infection with the Middle East Respiratory Syndrome-related coronavirus (MERS-CoV).
Read More...Gene expression profiling of MERS-CoV-London strain
In this study, the authors identify transcripts and gene networks that are changed after infection with the Middle East Respiratory Syndrome-related coronavirus (MERS-CoV).
Read More...Association of depression and suicidal ideation among adults with the use of H2 antagonists
In this study, the authors investigate associations between use of histamine H2 receptor antagonists and suicidal ideation in different age groups.
Read More...Reducing levels of C-Reactive Protein: An eight-week, open-label clinical trial of three oral supplements
In this study, the effects of vitamin C, ginger, or curcumin supplements on C-reactive protein levels in healthy participants are determined in an eight-week open-label trial.
Read More...Novel biaryl imines and amines as potential competitive inhibitors of dihydropteroate synthase
In this study, the authors design a series of new biaryl small molecules to target and block the binding pocket of the enzyme dihydropteroate synthase, which is important for prokaryotic biosynthesis of folic acid and could serve as better antimicrobial compounds.
Read More...Investigating the Role of the Novel ESCRT-III Recruitment Factor CCDC11 in HIV Budding: A Potential Target for Antiviral Therapy
Acquired immunodeficiency syndrome (AIDS) is a life-threatening condition caused by the human immunodeficiency virus (HIV). In this work, Takemaru et al explored the role of Coiled-Coil Domain-Containing 11 (CCDC11) in HIV-1 budding. Their results suggest that CCDC11 is critical for efficient HIV-1 budding, potentially indicating CCDC11 a viable target for antiviral therapeutics without major side effects.
Read More...Effect of pH Change on Exoskeletons of Selected Saltwater Organisms Which Rely on Calcium Fixation
Rising atmospheric carbon dioxide levels are projected to lead to a 0.3- 0.4 unit decrease in ocean surface pH levels over the next century. In this study, the authors investigate the effect of pH change on the mass of calcified exoskeletons of common aquatic organisms found in South Florida coastal waters.
Read More...EEG study of virtual learning demonstrates worsened learning outcomes and increased mirror neuron activation
In this article, Choi and Rossitto investigated the limitations of virtual learning by examining in-person dance learning compared to virtual dance learning while wearing EEG headsets. They found that in-person learners outperformed virtual learners and that virtual learners had higher mirror neuron activity as assessed by Mu rhythm power.
Read More...In vitro Comparison of Anticancer and Immunomodulatory Activities of Resveratrol and its Oligomers
Resveratrol is a type of stillbenoid, a phenolic compound produced in plants, that is known for its anti-inflammatory and anticancer effects. Many oligomers of resveratrol have recently been isolated their bioactivities remain unknown. Here, authors compared the bioactivities of resveratrol with natural dimers (ε-viniferin and gnetin H) and trimers (suffruticosol B and C). Results provide preliminary evidence that resveratrol oligomers could be potential preventive or therapeutic agents for cancers and other immune-related diseases
Read More...Linear and non-linear summation of responses to visual and olfactory cues in male Drosophila melanogaster
In this study, the authors investigate whether phototaxis and odortaxis in Drosophila melanogaster occurs through linear summation of cues including light and attractive odorants.
Read More...Optimizing 3D printing parameters: Evaluating infill type and layer height effects on tensile fracture force
In this study, the authors test different infill patterns to determine which would be the strongest and most durable for 3D printing applications, which have become an integral part of many facets of life.
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