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Applying centrality analysis on a protein interaction network to predict colorectal cancer driver genes

Saha et al. | Nov 18, 2023

Applying centrality analysis on a protein interaction network to predict colorectal cancer driver genes

In this article the authors created an interaction map of proteins involved in colorectal cancer to look for driver vs. non-driver genes. That is they wanted to see if they could determine what genes are more likely to drive the development and progression in colorectal cancer and which are present in altered states but not necessarily driving disease progression.

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A Retrospective Study of Research Data on End Stage Renal Disease

Ponnaluri et al. | Mar 09, 2016

A Retrospective Study of Research Data on End Stage Renal Disease

End Stage Renal Disease (ESRD) is a growing health concern in the United States. The authors of this study present a study of ESRD incidence over a 32-year period, providing an in-depth look at the contributions of age, race, gender, and underlying medical factors to this disease.

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Retinal biomarkers for the detection of neurological disease using deep learning

Kim et al. | Sep 04, 2026

Retinal biomarkers for the detection of neurological disease using deep learning

The authors looked at whether retinal features, specifically lens clarity, optic nerve cupping, and hyperreflective foci, can serve as biomarkers for neuro-ophthalmological diseases, which share pathological mechanisms with neurodegeneration and may indicate broader neurological risk. Using multimodal clinical data and machine learning, they investigated the potential of retinal imaging as a complementary diagnostic tool for more accurate and accessible detection of neurological disorders.

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Global trends in total cholesterol by gender (1980-2018)

Qi et al. | Aug 24, 2026

Global trends in total cholesterol by gender (1980-2018)

This study explores global trends in average total cholesterol levels among adults from 1980 to 2018, finding a significant decline in both men and women, with a sharper decrease among men. While these improvements likely reflect advances in public health and medical treatment, the persistent gender gap highlights the need for more targeted approaches to cardiovascular disease prevention.

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