Browse Articles

Development of anti-cancer bionanoparticles isolated from corn for bone cancer treatment

Richardson et al. | Apr 20, 2023

Development of anti-cancer bionanoparticles isolated from corn for bone cancer treatment

This study hypothesizes that nanoparticles derived from corn (cNPs)may have anti-proliferative effects on bone cancer and metastasized bone cancer. It finds that human osteosarcoma and human lung carcinoma metastasized to bone marrow cell viability decreased to 0% when treated with cNPs. Overall, these results indicate that cNPs have anti-proliferative effects on bone cancer cells and cancer cells that metastasize to the bone.

Read More...

Machine learning-based enzyme engineering of PETase for improved efficiency in plastic degradation

Gupta et al. | Jan 31, 2023

 Machine learning-based enzyme engineering of PETase for improved efficiency in plastic degradation
Image credit: Markus Spiske

Here, recognizing the recognizing the growing threat of non-biodegradable plastic waste, the authors investigated the ability to use a modified enzyme identified in bacteria to decompose polyethylene terephthalate (PET). They used simulations to screen and identify an optimized enzyme based on machine learning models. Ultimately, they identified a potential mutant PETases capable of decomposing PET with improved thermal stability.

Read More...

Investigating facilitated biofilm formation in Escherichia coli exposed to sublethal levels of ampicillin

Yang et al. | Jan 20, 2023

Investigating facilitated biofilm formation in <em>Escherichia coli</em> exposed to sublethal levels of ampicillin

Here, the authors recognized the tendency of bacteria to form biofilms, where this behavior offers protection against threats such as antibiotics. To investigate this, they observed the effects of sublethal exposure of the antibiotic ampicillin on E. coli biofilm formation with an optical density crystal violet assay. They found that exposure to ampicillin resulted in the favored formation of biofilms over time, as free-floating bacteria were eradicated.

Read More...

The impact of COVID-19 quarantine on physical activities in Basra, Iraq: A cross-sectional study

Al Saeedi et al. | Aug 30, 2022

The impact of COVID-19 quarantine on physical activities in Basra, Iraq: A cross-sectional study

As the COVID-19 pandemic continues, the authors noticed a change in the physical activity of many people, as well as a change in the type of physical activity they practice. Here, the authors used a cross-sectional survey of 150 participants from the province of Basra in Iraq. They found an overall decrease in the number of days of physical activity for participants along with an increasing proportion of at-home exercises compared to other activities that are performed inside sports clubs during the pandemic.

Read More...

Anticancer, anti-inflammatory, and apoptotic activities of MAT20, a poly-herbal formulation.

Kashyap Jha et al. | Mar 29, 2022

Anticancer, anti-inflammatory, and apoptotic activities of MAT20, a poly-herbal formulation.

Kashyap Jha et al. look at the formulation of MAT20, a crude extract of the moringa, amla, and tulsi leaves, as a potential complementary and alternative medicine. Using HeLa cells, they find MAT20 up-regulates expression of inflammation and cell cytotoxicity markers. Their data is important for understanding the anti-cancer and anti-inflammatory properties of MAT20.

Read More...

Correlation between shutdowns and CO levels across the United States.

Gupta et al. | Dec 05, 2021

Correlation between shutdowns and CO levels across the United States.

Concerns regarding the rapid spread of Sars-CoV2 in early 2020 led company and local governmental officials in many states to ask people to work from home and avoid leaving their homes; measures commonly referred to as shutdowns. Here, the authors investigate how shutdowns affected carbon monoxide (CO) levels in 15 US states using publicly available data. Their results suggest that CO levels decreased as a result of these measures over the course of 2020, a trend which started to reverse after shutdowns ended.

Read More...

The Potential of Fibroblast Growth Factors to Stimulate Hair Growth In Vitro

Cheng et al. | Nov 07, 2021

The Potential of Fibroblast Growth Factors to Stimulate Hair Growth In Vitro

Identifying treatments that can stimulate hair growth use could help those struggling with undesirable hair loss. Here, the authors show that Fibroblast Growth Factors can stimulate the division of cells isolated from the mouse hair follicle. Their results suggest that this family of growth factors might be helpful in stimulating hair growth in living animals as well.

Read More...