Cancer is often caused by improper function of a few proteins, and sometimes it takes only a few proteins to malfunction to cause drastic changes in cells. Here the authors look at the genes that were mutated in patients with a type of pancreatic cancer to identify proteins that are important in causing cancer. They also determined which proteins currently lack effective treatment, and suggest that certain proteins (named KRAS, CDKN2A, and RBBP8) are the most important candidates for developing drugs to treat pancreatic cancer.

Agricultural fertilizer application is a key innovation in providing enough food to feed the world. Fertilizers come in various types and farmers must choose which fertilizer is the best for their applications. To learn more about the effectiveness of various fertilizers, Wilson and Rasmus studied the effects of natural and chemical fertilizers on growth of basil plants.

The authors test potential anti-inflammatory and pro-apoptotic effects of a polyherbal extract formulation on cultured breast cancer cells.

Fear of mathematics is a widespread phenomenon. Pandey and Pandey investigate what this fear has to do with the place of mathematics in a school curriculum, by developing a method for comparing mathematical problem complexity to the complexity of English literature coursework.

The purpose of this investigation is to develop a hydrogel to aid skin regeneration by creating an extracellular matrix for fibroblast growth with antibacterial and infection-detection properties. Authors developed two natural hydrogels based on pectin and potato peels and characterized the gels for fibroblast compatibility through rheology, scanning electron microscopy, swelling, degradation, and cell cytotoxicity assays. Overall, this experiment fabricated various hydrogels capable of acting as skin substitutes and counteracting infections to facilitate wound healing. Following further testing and validation, these hydrogels could help alleviate the 13-billion-dollar financial burden of foot ulcer treatment.

A bottleneck in deleting algal blooms is that current data section is manual and is reactionary to an existing algal bloom. These authors made a custom-designed Seek and Destroy Algal Mitigation System (SDAMS) that detects harmful algal blooms at earlier time points with astonishing accuracy, and can instantaneously suppress the pre-bloom algal population.

The authors found that treatment with AS20 suppressed phorbol 12-myristate 13-acetate (PMA) and 5-flurouracil (5-FU) induction of COX2 expression. We also observed AS20 treated cells showed DNA fragmentation in HeLa cells.

The authors looked at renewable energy generators and the ability to utilize green roofs as a solution to climate change.

In this study, three models are used to test the hypothesis that data-centric artificial intelligence (AI) will improve the performance of machine learning.

Counterintuitive in nature, the Mpemba effect asserts that hot liquid freezes faster than cold liquid. While noted throughout history by scientific minds like Aristotle, the phenomenon remains in contention with varying hypotheses for the effect proposed alongside the effect’s rise in popularity. Contributing to the research efforts surrounding the Mpemba effect, the authors in this article explore the effect in different liquids ranging in physical properties and intermolecular forces to determine potential parameters attributable to producing the Mpemba effect.