Browse Articles

Authors emphasize the challenges of manual tumor segmentation and the potential of deep learning models to enhance accuracy by automatically analyzing MRI scans.

In this study, the authors looked at a proto-oncogene, KRAS, and searched for molecules that are predicted to be able to bind to the inactive form of KRAS. They found that a modified version of Irbesartan, a derivative of benzimidazole, showed the best binding to inactive KRAS.

Wang and Gong developed a novel dynamic gene-searching algorithm called Dynamic Gene Search (DyGS) to create a gene panel for each of the 12 cancers with the highest annual incidence and death rate. The 12 gene panels the DyGS algorithm selected used only 3.5% of the original gene mutation pool, while covering every patient sample. About 40% of each gene panel is druggable, which indicates that the DyGS-generated gene panels can be used for early cancer detection as well as therapeutic targets in treatment methods.

This study combines gene expression, mutation profiling, and survival analysis of 17 clinically important genes in breast cancer, utilizing the TCGA-BRCA dataset. Our results show that there are different patterns of oncogene upregulation, different levels of tumor suppressor activity, and complicated survival associations. TP53 was the most frequently mutated gene in this cohort. The results underscore the significance of multidimensional genomic analyses for a comprehensive understanding of breast cancer biology and its therapeutic ramifications.

The authors combine fine needle aspiration biopsy and machine learning algorithms to develop a breast cancer detection method suitable for resource-constrained regions that lack access to mammograms.

The authors looked at the impact of citrate and lactate on glioblastoma progression. Their results provide important insights for future immunotherapies aimed at treating glioblastoma.

The authors looked at the ability of different deep learning models to predict the presence of lung cancer from chest CT scans. They found that a pre-trained CNN model performed better than an autoencoder model.

This study compares the performance of two deep learning models, U-Net and DeconvNet, for segmenting gliomas from MRI scans.

In this study, the authors identify new potential targets to treat advanced diffuse large B-cell lymphoma after treatment relapse and loss of CD19 expression.

This study follows the process of single-cloning and the growth of a homogeneous cell population in a superficial environment over the course of six weeks with the end goal of showing which of five tumor growth models commonly used to predict heterogeneous cancer cell population growth (Exponential, Logistic, Gompertz, Linear, and Bertalanffy) would also best exemplify that of homogeneous cell populations.