In this study, the authors investigate the effect of a herbal formulation on Cyclooxygenase-2 (COX-2) expression in cancer cells. High levels of COX-2 correlates with worsened cancer outcomes and the authors hypothesize that the formulation will inhibit COX-2 levels.

In this study, the authors determine optimal pH levels for maximizing isopropanol degradation in water. This has important applications for cleaning up polluted wastewater in the environment.

In this study, the authors engineer a cost-effective and bio-friendly water purification system using limestone, denitrifying bacteria, and sulfate-reducing bacteria. They evaluated its efficacy with samples from Eastern PA industrial sites.

Although no comprehensive characterization of schizophrenia exists, there is a general consensus that patients have electrical dysfunction in the prefrontal cortex. The authors designed a novel piezoelectric silk-based implant and optimized electrical output through the addition of conductive materials zinc oxide (ZnO) and aluminum nitride (AlN). With further research and compatibility studies, this implant could rectify electrical misfiring in the infralimbic prefrontal cortex.

Glioblastoma is a brain cancer caused by the presence of a fast-growing, malignant tumor in the brain. As of now, this cancer is universally lethal due to lack of efficacious treatment options. C-C chemokine receptor 1 (CCR1) is a G-protein coupled receptor that controls chemotaxis, the movement of cells in response to chemical stimuli. This research aims to synthesize potential CCR1 antagonists by coupling carboxylic acids with a triazole core. We synthesized these compounds using a simple carboxylic acid coupling and confirmed the identity of the final compounds using nuclear magnetic resonance (NMR) spectroscopy.

Fertilizers are commonly used to improve agricultural yield. Unfortunately, chemical fertilizers can seep into drinking water, potentially harming humans and other forms of life. Here, the authors investigate the effect of fertilizer on the water quality of Saratoga Creek over time. They find that fertilizers can alter the acidity of the creek's water, which can be harmful to aquatic species, as well as increase the levels of nitrates temporarily.

While 75% of waste in the United States is stated to be recyclable, only about 34% truly is. This project takes a stance to combat the pillars of mismanaged waste through a modern means of convenience: the TracedWaste app. The purpose of this study was to identify how individuals' waste disposal habits improved and knowledge increased (i.e. correctly disposing of waste, understanding negative incorrect waste disposal) due to their use of an informational waste management app as measured by a survey using a 1-5 Likert Scale. The results showed that the TracedWaste app helped conserve abundant resources such as energy and wood, decrease carbon emissions, and minimize financial toll all through reducing individual impact.

Mainstream cancer treatments, which include radiotherapy and chemotherapeutic drugs, are known to induce oxidative damage to healthy somatic cells due to the liberation of harmful free radicals. In order to avert this, physiological antioxidants must be complemented with external antioxidants. Here the authors performed a preliminary phytochemical screen to identify alkaloids, saponins, flavonoids, polyphenols, and tannins in all parts of the Amaranthus spinosus Linn. plant. This paper describes the preparation of this crude extract and assesses its antioxidant properties for potential use in complementary cancer treatment.

In this study, the authors test whether a gravity vehicle, which is a vehicle powered by its own gravity on a ramp, could be designed to move faster when mathematical calculations for optimal mass and center of gravity were applied in the design.

In this study, the authors investigate the suitability of using bacterial cellulose as a scaffold for cell transplants. Interestingly, this cellulose is a can be found in the discard from a symbiotic culture of bacteria and yeast (SCOBY) used to make kombucha.