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Impact of daf-25 and daf-11 Mutations on Olfactory Function in C. elegans

Gardner et al. | Feb 02, 2019

Impact of daf-25 and daf-11 Mutations on Olfactory Function in C. elegans

Cilia are little hair-like protrusions on many cells in the human body, including those lining the trachea where they play a role in clearing our respiratory tract of mucous and other irritants. Genetic mutations that impair ciliary function have serious consequences on our well-being making it important to understand how ciliary function is regulated. By using a simple organism, such as the worm C. elegans that use cilia to move, the authors explore the effect of certain genetic mutations on the cilia of the worms by measuring their ability to move towards or away from certain odorants.

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Sports Are Not Colorblind: The Role of Race and Segregation in NFL Positions

Coleman et al. | Oct 23, 2018

Sports Are Not Colorblind: The Role of Race and Segregation in NFL Positions

In this study, the authors conducted a statistical investigation into the history of position-based racial segregation in the NFL. Specifically, they focused on the cornerback position, which they hypothesized would be occupied disproportionately by black players due to their historical stereotyping as more suitable for positions requiring extreme athletic ability. Using publicly available datasets on the demographics of NFL players over the past several decades, they confirmed their hypothesis that the cornerback position is skewed towards black players. They additionally discovered that, unlike in the quarterback position, this trend has shown no sign of decreasing over time.

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The Role of Temporal Lobe Epilepsy in Cardiac Structure and Function

Choi et al. | Aug 15, 2018

The Role of Temporal Lobe Epilepsy in Cardiac Structure and Function

Cardiac autonomic and structural changes may occur in temporal lobe epilepsy patients and contribute to the risk of sudden unexpected death in epilepsy patients. Choi and colleagues reviewed clinical charts to obtain patients’ lifetime seizure count, antiepileptic drug use, and history of heart disease, followed by transthoracic echocardiogram to calculate left ventricle dimensions, ejection fraction, and left ventricle mass. By comparing epilepsy patients to control subjects, they found that epilepsy patients had thinner left ventricle walls and smaller ejection fraction, but with no significant difference in left ventricle mass.

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Effect of Natural Compounds Curcumin and Nicotinamide on α-synuclein Accumulation in a C. elegans Model of Parkinson’s Disease

Mehrotra et al. | Jan 29, 2018

Effect of Natural Compounds Curcumin and Nicotinamide on α-synuclein Accumulation in a C. elegans Model of Parkinson’s Disease

Parkinson's disease is a neurodegenerative disorder that affects over 10 million people worldwide. It is caused by destruction of dopamine-producing neurons, which results in severe motor and movement symptoms. In this study, the authors investigated the anti-Parkinsonian effects of two natural compounds curcumin and nicotinamide using C. elegans as a model organism.

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Bacteroides thetaiotaomicron Growth Numbers Are Unchanged in the Presence of Yogurt

Phan et al. | Dec 29, 2016

<i>Bacteroides thetaiotaomicron</i> Growth Numbers Are Unchanged in the Presence of Yogurt

Disruptions to the microbiome, specifically the imbalance in the two major phyla, the Firmicutes and the Bacteroidetes, have been linked to the development of obesity. This study explored whether or not Fage plain total 0% Greek yogurt, which contains live and active bacterial cultures belonging to the Firmicute phylum, could decrease the numbers of Bacteroides thetaiotaomicron, an organism found in the human gut that belongs to the Bacteroidetes phylum.

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