The authors computationally screened potential ALDH1 inhibitors, for use as potential cancer therapeutics.
Read More...In silico screening of DEAB analogues as ALDH1 isoenzymes inhibitors in cancer treatment
The authors computationally screened potential ALDH1 inhibitors, for use as potential cancer therapeutics.
Read More...The effects of varied N-acetylcysteine concentration and electronegativity on bovine mucus hydrolysis
The authors evaluated the effect of concentration and variant of N-Acetylcysteine in hydrolyzing mucus.
Read More...Investigating the impact of short-chain fatty acids on myofiber dynamics and insulin sensitivity
The authors looked at the impacts of short-chain fatty acids on muscle fiber formation as well as insulin sensitivity using a model of mouse myoblasts.
Read More...The effect of common food preservatives on the growth of bacteria
Here the authors aimed to find the best preservative combinations to stop bacterial growth in food, using data modeling and biochemical experiments. They discovered that single preservatives are often not enough, with varying effectiveness against different bacteria, and suggest future research into combining preservatives for better results.
Read More...The effects of cochineal and Allura Red AC dyes on Escherichia coli and Bacillus coagulans growth
Here the authors aimed to compare the effects of artificial Allura Red AC dye and natural cochineal dye on the growth of Escherichia coli and Bacillus coagulans bacteria. Their research found that only Allura Red AC dye significantly affected bacterial growth, specifically amplifying E. coli growth. Based on their results, they suggest that Allura Red AC dye may increase the growth of E. coli bacteria within the human gut.
Read More...Citrate and lactate drive glioblastoma progression via activation of tumor-associated macrophages
The authors looked at the impact of citrate and lactate on glioblastoma progression. Their results provide important insights for future immunotherapies aimed at treating glioblastoma.
Read More...Chemoreception in Aurelia aurita studied by AI-enhanced image analysis
The authors studied the chemoreception of moon jellyfish in response to food, and developed an AI tool to identify track and quantify the pulsation of swimming jellyfish.
Read More...An assessment of controllable etiological factors involved in neonatal seizure using a Monte Carlo model
The authors used Monte Carlo simulations to assess the impacts of various factors on neonatal seizure risk.
Read More...Relationship between p62 and learning behavior in male and female mice deficient in hippocampal folliculin
Here the authors hypothesized that reducing folliculin (FLCN) might affect p62 protein levels in the dorsal hippocampus of mice, given their potential functional connection and p62's role in neurodegenerative diseases. Their study, using western blots and a two-way ANOVA on young wild-type mice, found that p62 levels correlated with FLCN expression, but ultimately concluded there's no evidence of a functional connection between FLCN and p62 in this specific model.
Read More...Effect of environmental factors on bacterial flora of normal human skin
The authors looked how different working conditions impacted the microbiome of the human skin.
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