The authors designed a system that runs off of body heat to track body temperature that could help prevent injuries that result from elevated body temperature.
Read More...Developing a wearable, skin-based triboelectric nanogenerator
The authors designed a system that runs off of body heat to track body temperature that could help prevent injuries that result from elevated body temperature.
Read More...Prediction of preclinical Aβ deposit in Alzheimer’s disease mice using EEG and machine learning
Alzheimer’s disease (AD) is a common disease affecting 6 million people in the U.S., but no cure exists. To create therapy for AD, it is critical to detect amyloid-β protein in the brain at the early stage of AD because the accumulation of amyloid-β over 20 years is believed to cause memory impairment. However, it is difficult to examine amyloid-β in patients’ brains. In this study, we hypothesized that we could accurately predict the presence of amyloid-β using EEG data and machine learning.
Read More...The effects of COVID-19 pandemic social isolation on the mental and physical health of the general population
Here, seeking to better understand on the effects of social isolation during the COVID-19 pandemic, the authors used a survey during April and May of 2020 of participants primarily in Long Island, NY to assess the physical and mental health of the general population. They found negative impacts to physical health and increases in depressive symptoms and feelings of loneliness across all groups. More significant increases in negative mental health symptoms were observed in younger age groups and amongst women.
Read More...Characterizing the association between hippocampal reactive astrogliosis, anhedonia-like behaviors, and neurogenesis in a monkey model of stress and antidepressant treatment
This study examined the effects of stress and selective serotonin reuptake inhibitors (SSRIs) on a measure of astrocyte reactivity in nonhuman primate (NHP) models of stress. Results showed that chronic separation stress in NHPs leads to increased signs of astrogliosis in the NHP hippocampus. The findings were consistent with the hypotheses that hippocampal astrogliosis is an important mechanism in stress-induced cognitive and behavioral deficits.
Read More...Examining the relationship between screen time and achievement motivation in an adolescent population
In this study, the authors conduct a survey of high school students to evaluate the effects of screen time and habits on motivation.
Read More...Ribosome distribution affects stalling in amino-acid starved cancer cells
In this article, the authors analyzed ribosome profiling data from amino acid-starved pancreatic cancer cells to explore whether the pattern of ribosome distribution along transcripts under normal conditions can predict the degree of ribosome stalling under stress. The authors found that ribosomes in amino acid-deprived cells stalled more along elongation-limited transcripts. By contrast, they observed no relationship between read density near start and stop and disparities between mRNA sequencing reads and ribosome profiling reads. This research identifies an important relationship between read distribution and propensity for ribosomes to stall, although more work is needed to fully understand the patterns of ribosome distribution along transcripts in ribosome profiling data.
Read More...Correlation between shutdowns and CO levels across the United States.
Concerns regarding the rapid spread of Sars-CoV2 in early 2020 led company and local governmental officials in many states to ask people to work from home and avoid leaving their homes; measures commonly referred to as shutdowns. Here, the authors investigate how shutdowns affected carbon monoxide (CO) levels in 15 US states using publicly available data. Their results suggest that CO levels decreased as a result of these measures over the course of 2020, a trend which started to reverse after shutdowns ended.
Read More...Genomic Signature Analysis for the Strategic Bioremediation of Polycyclic Aromatic Hydrocarbons in Mangrove Ecosystems in the Gulf of Tonkin
Engineered bacteria that degrade oil are currently being considered as a safe option for the treatment of oil spills. For this approach to be successful, the bacteria must effectively express oil-degrading genes they uptake as part of an external genoming vehicle called a "plasmid". Using a computational approach, the authors investigate plasmid-bacterium compatibility to find pairs that ensure high levels of gene expression.
Read More...Testing HCN1 channel dysregulation in the prefrontal cortex using a novel piezoelectric silk neuromodulator
Although no comprehensive characterization of schizophrenia exists, there is a general consensus that patients have electrical dysfunction in the prefrontal cortex. The authors designed a novel piezoelectric silk-based implant and optimized electrical output through the addition of conductive materials zinc oxide (ZnO) and aluminum nitride (AlN). With further research and compatibility studies, this implant could rectify electrical misfiring in the infralimbic prefrontal cortex.
Read More...The Protective Antioxidant Effects of Sulforaphane on Germinating Radish Seeds Treated with Hydrogen Peroxide
Free radical chain reactions result when atoms containing unpaired electrons bind with biomolecules and alter their biological functions, contributing to the progression of diseases such as atherosclerosis, cancer, and diabetes. Antioxidants, such as vitamin E and sulforaphane, are effective neutralizers of free radicals and prevent cellular damage. This present study is conducted to determine the relative effectiveness of sulforaphane against free radicals generated by hydrogen peroxide (H2O2) compared with the known antioxidant vitamin E.
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