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The Effect of Ultraviolet Radiation and the Antioxidant Curcumin on the Longevity, Fertility, and Physical Structure of Drosophila melanogaster: Can We Defend Our DNA?

Lateef et al. | May 18, 2019

The Effect of Ultraviolet Radiation and the Antioxidant Curcumin on the Longevity, Fertility, and Physical Structure of <em>Drosophila melanogaster</em>: Can We Defend Our DNA?

Ultraviolet (UV) radiation is known to alter DNA structure and impair cellular function in all living organisms. In this study, Lateef et al examine the effects of UV radiation to determine whether antioxidant-enriched nutrition can combat the potential deleterious effects of UV radiation on Drosophila melanogaster. They found that UVB (320nm) radiation caused a 59% decrease in the Drosophila lifespan and mutagenic effects on flies' physical appearance, but did not significantly affect fertility. Curcumin significantly prolonged lifespan and enhanced fertility for both UV- and non-UV-exposed flies. The research demonstrates the positive potential of natural antioxidants as weapons against radiation-induced diseases including cancer.

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The Development of a Highly Sensitive Home Diagnosis Kit for Group A Streptococcus Bacteria (GAS)

Mai et al. | Dec 05, 2018

The Development of a Highly Sensitive Home Diagnosis Kit for Group A Streptococcus Bacteria (GAS)

In this article, Mai et al. have developed a do-it-yourself kit for the detection of Strep A bacterial infections. While Strep A infections require antibiotic administration, viral infections, which can present with similar symptoms, often resolve on their own. The problem with delayed antibiotic treatment is an increasing risk of complications. Currently an accurate diagnosis requires that patients make the trip to the hospital where sensitive tests can be performed. The method described here, bundled into a commercially available kit, could help speed up the identification of such bacterial infections. When presented with symptoms of a sore throat and fever, you could just buy the kit at your local pharmacy, perform the simple yet highly accurate and sensitive test, and know whether an urgent trip to the doctor's for an antibiotic prescription is necessary. How convenient!

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Improving Wound Healing by Breaking Down Biofilm Formation and Reducing Nosocomial Infections

DiStefano et al. | Jul 09, 2019

Improving Wound Healing by Breaking Down Biofilm Formation and Reducing Nosocomial Infections

In a 10-year period in the early 2000’s, hospital-based (nosocomial) infections increased by 123%, and this number is increasing as time goes on. The purpose of this experiment was to use hyaluronic acid, silver nanoparticles, and a bacteriophage cocktail to create a hydrogel that promotes wound healing by increasing cell proliferation while simultaneously disrupting biofilm formation and breaking down Staphylococcus aureus and Pseudomonas aeruginosa, which are two strains of bacteria that attribute to nosocomial infections and are increasing in antibiotic resistance.

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The impacts of different Al(NO3)3 concentrations on the mitotic index of Allium sativum

Jimenez Pol et al. | Jul 10, 2023

The impacts of different Al(NO<sub>3</sub>)<sub>3</sub> concentrations on the mitotic index of <i>Allium sativum</i>
Image credit: Kylie Paz

Recognizing the increasing threat of acid deposition inn soil through the reaction of NOx and SO2 pollutants with water in Spain, the authors investigates the effects of Al(NO3)3 concentrations on the health of Allium sativum. By tracking its mitotic index, they found a negative exponential correlation between Al(NO3)3 concentrations and the mitotic index of A. sativum.

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Zinc-related Treatments Combined with Chloroquine and Gemcitabine for Treating Pancreatic Cancer

Ma et al. | Sep 11, 2021

Zinc-related Treatments Combined with Chloroquine and Gemcitabine for Treating Pancreatic Cancer

Pancreatic cancer is one of the deadliest cancers, with a 10% 5-year survival rate. The authors studied various dosages of TPEN and zinc in combination with Chloroquine and Gemcitabine as treatments to reduce cell proliferation. Results showed that when combined with Chloroquine and Gemcitabine, zinc and TPEN both significantly lowered cell proliferation compared to Gemcitabine, suggesting a synergistic effect that resulted in a more cytotoxic treatment. Further research and clinical trials on this topic are needed to determine whether this could be a viable treatment for pancreatic cancer.

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Effects of Paan Extracts on Periodontal Ligament and Osteosarcoma Cells

Venkatachalam et al. | Sep 20, 2018

Effects of Paan Extracts on Periodontal Ligament and Osteosarcoma Cells

In South Asian countries, the major cause of oral cancer is reported to be chewing paan, which is comprised of betel leaf daubed with slaked lime paste and areca nut. To investigate how paan may contribute to the onset of cancer, the authors treated two immortalized cell lines with extracts of betel leaf, areca nut, and lime and evaluated how these treatments affected cell proliferation and cell death. Initial results indicate that while betel leaf alone may inhibit cell growth, areca nut promoted cancer cell survival and proliferation, even when co-treated with betel leaf. These data suggest that areca nut could exacerbate the progression of oral cancer in humans.

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Assessing Attitude Across Different Age Groups in Regard to Global Issues: Are Kids More Optimistic Than Adults?

Luck et al. | Jan 11, 2020

Assessing Attitude Across Different Age Groups in Regard to Global Issues: Are Kids More Optimistic Than Adults?

In this article the authors investigate whether there is a correlation between age of a person and their outlook on global issues such as technology, politics, and environment. They find a correlation between increased age and decreased optimism. However regardless of age, they find that respondents believe certain characteristics such as technology and willingness to change are essential for improvements.

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Sri Lankan Americans’ views on U.S. racial issues are influenced by pre-migrant ethnic prejudice and identity

Gunawardena et al. | Apr 18, 2022

Sri Lankan Americans’ views on U.S. racial issues are influenced by pre-migrant ethnic prejudice and identity

In this study, the authors examined how Sri Lankan Americans (SLAs) view racial issues in the U.S. The main hypothesis is that SLAs, as a minority in the U.S., are supportive of the Black Lives Matter movement and its political goal, challenging the common notion that SLAs are anti-Black. The study found that a majority of SLAs believe the U.S. has systemic racism, favor BLM, and favor affirmative action. IT also found that Tamil SLAs have more favorable views of BLM and affirmative action than Sinhalese SLAs.

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Tap water quality analysis in Ulaanbaatar City

Munkhbat et al. | Sep 25, 2022

Tap water quality analysis in Ulaanbaatar City

There have been several issues concerning the water quality in Ulaanbaatar, Mongolia in the past few years. This study, we collected 28 samples from 6 districts of Ulaanbaatar to check if the water supply quality met the standards of the World Health Organization, the Environmental Protection Agency, and a Mongolian National Standard. Only three samples fully met all the requirements of the global standards. Samples in Zaisan showed higher hardness (>120 ppm) and alkalinity levels (20–200 ppm) over the other districts in the city. Overall, the results show that it is important to ensure a safe and accessible water supply in Ulaanbaatar to prevent future water quality issues.

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