In this article the authors address the complex and life quality-diminishing neurodegenerative disease known as Parkinson's. Although genetic and/or environmental factors contribute to the etiology of the disease, the diagnostic symptoms are the same. By genetically modifying fruit flies to exhibit symptoms of Parkinson's disease, they investigate whether drugs that inhibit mitochondrial calcium uptake or activate the lysosomal degradation of proteins could improve the symptoms of Parkinson's these flies exhibit. The authors report the most promising outcome to be that when both types of drugs were used together. Their data provides encouraging evidence to support further investigation of the utility of such drugs in the treatment of human Parkinson's patients.

Here the authors investigate the use of social media in adults with Autism Spectrum Disorder (ASD) in affecting their ability and opportunities to interact with others. They found that higher usage of Internet correlated with less severe anxiety symptoms and improved social skills.

Climate records indicate that there has been a trend of decreasing annual snowfall totals throughout the United States during the peak winter season. However, New Jersey has seen a significant increase in snowfall over the past 126 years of recorded observations. The authors hypothesize that although annual snowfall has remained the same on average, the frequencies of major and minor snowfall events have noticeably increased. They found that there was no significant evidence for an increase in the frequency of minor events (1.1-inch to 4.0-inch events), but there was evidence for an increase in the frequency of major events (4.1+ inch events). The results imply that a warming climate might be opening up opportunities for more snowfall.

Lithium-ion batteries, a breakthrough in chemistry that enabled the electronic revolution we live today have become an essential part of our day-to-day life. A phone battery running out after a heavy day of use with limited opportunities for recharging is a well-known and resented experience by almost everyone. How then can we make batteries more efficient? This paper proposes the use of a different type of separator, that improves the charging and discharging capacities of lithium ions compared to the classical separator. This and similar attempts to improve Lithium-ion battery function could facilitate the development of higher-performance batteries that work longer and withstand harsher use.

Recent research suggests that the "American Dream" of income mobility may be becoming increasingly hard to obtain. Datta and Schmitz explore the role of government spending in socioeconomic opportunity by determining which state government spending components are associated with increased income mobility.

The purpose of this study was to investigate the relationship between colorism and police killings of unarmed African American suspects. The authors collected data from the Washington Post database, which reports unarmed African American victims from 2015–2021, and found that the victims who were killed by police were darker on average than a control population of African Americans that had not encountered the police.

The authors looked at previous studies to evaluate the ability to use serum levels of certain cytokines as biomarkers for pneumoconiosis.

Major Depressive Disorder (MDD), and Post-Traumatic Stress Disorder (PTSD) are two of the fastest growing comorbid diseases in the world. Using publicly available datasets from the National Institute for Biotechnology Information (NCBI), Ravi and Lee conducted a differential gene expression analysis using 184 blood samples from either control individuals or individuals with comorbid MDD and PTSD. As a result, the authors identified 253 highly differentially-expressed genes, with enrichment for proteins in the gene ontology group 'Ribosomal Pathway'. These genes may be used as blood-based biomarkers for susceptibility to MDD or PTSD, and to tailor treatments within a personalized medicine regime.

This study's goal was to identify the Mach numbers for which electrostatic drag and heat transfer manipulation would be most applicable inside the stratosphere. The experiments were conducted using computational fluid dynamics software. The study demonstrated that, on average, higher Mach speeds resulted in a considerably higher potential decrease in density. The study highlights that further research on the surface charge method is warranted to explore higher hypersonic speeds within the stratosphere.

This study compares different methods for cooking vegetables to determine which retain iron and ascorbic acid, or vitamin C, levels the most.