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Association of agenesis of the corpus callosum with epilepsy and anticonvulsant drug treatment

Steger et al. | Feb 21, 2023

Association of agenesis of the corpus callosum with epilepsy and anticonvulsant drug treatment
Image credit: Robina Weermeijer on Unsplash

Agenesis of the Corpus Callosum (ACC) is a birth defect where an infant’s corpus callosum, the structure linking the brain’s two hemispheres to allow interhemispheric communication, fails to develop in a typical manner during pregnancy. Existing research on the connection between ACC and epilepsy leaves significant gaps, due to the lack of focused investigation. One important gap is the degree to which ACC may impact the course of epilepsy treatment and outcomes. The present study was conducted to test the hypotheses that epilepsy is highly prevalent among individuals with ACC, and that those with both ACC and epilepsy have a lower response rate to anticonvulsant drugs than other patients treated with anticonvulsant drugs. A weighted average of epilepsy rates was calculated from a review of existing literature, which supported the hypothesis that epilepsy was more common among individuals with ACC (25.11%) than in the general population (1.2%). An empirical survey administered to 57 subjects or parents of subjects showed that rate of intractable epilepsy among study subjects with both ACC and epilepsy was substantially higher than the rate found in the general population, indicating that individuals with both conditions had a lower response rate to the anticonvulsant drugs. This study contributes novel results regarding the potential for concurrence of ACC and epilepsy to interfere with anticonvulsant drug treatment. We also discuss implications for how medical professionals may use the findings of this study to add depth to their treatment decisions.

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Giving Teens a Voice: Sources of Stress for High School Students

Corson et al. | Sep 09, 2019

Giving Teens a Voice: Sources of Stress for High School Students

The authors investigate the negative effects stress has on teen mental and physical health. Through a survey, they give Virginia teens a voice in revising the Health and Physical Education curriculum to include a standards of learning (SOL). Notably they identify factors contributing to stress levels including homework level, amount of free and sleep time, parental pressure and family encouragement.

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An improved video fingerprinting attack on users of the Tor network

Srikanth et al. | Mar 31, 2022

An improved video fingerprinting attack on users of the Tor network

The Tor network allows individuals to secure their online identities by encrypting their traffic, however it is vulnerable to fingerprinting attacks that threaten users' online privacy. In this paper, the authors develop a new video fingerprinting model to explore how well video streaming can be fingerprinted in Tor. They found that their model could distinguish which one of 50 videos a user was hypothetically watching on the Tor network with 85% accuracy, demonstrating that video fingerprinting is a serious threat to the privacy of Tor users.

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Nintendo Da Vinci: A Novel Control System to Improve Performance in Robotic-Assisted Surgery

Al-Akash et al. | Oct 26, 2019

Nintendo Da Vinci: A Novel Control System to Improve Performance in Robotic-Assisted Surgery

Complications of robotic-assisted surgery are on the rise, partly due to surgeons not receiving proper training. Al-Akash and Al-Akash hypothesized Nintendo JoyCon controls would improve surgical performance compared to the FDA-approved Da Vinci Surgical System with two user groups (doctor and gamer). Their results show that implementing a Nintendo JoyCon control system is associated with improved surgical performance and learning rate compared to the Da Vinci Surgical System.

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Hybrid Quantum-Classical Generative Adversarial Network for synthesizing chemically feasible molecules

Sikdar et al. | Jan 10, 2023

Hybrid Quantum-Classical Generative Adversarial Network for synthesizing chemically feasible molecules

Current drug discovery processes can cost billions of dollars and usually take five to ten years. People have been researching and implementing various computational approaches to search for molecules and compounds from the chemical space, which can be on the order of 1060 molecules. One solution involves deep generative models, which are artificial intelligence models that learn from nonlinear data by modeling the probability distribution of chemical structures and creating similar data points from the trends it identifies. Aiming for faster runtime and greater robustness when analyzing high-dimensional data, we designed and implemented a Hybrid Quantum-Classical Generative Adversarial Network (QGAN) to synthesize molecules.

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A comparative study on the suitability of virtual labs for school chemistry experiments

Praveen et al. | Aug 22, 2022

A comparative study on the suitability of virtual labs for school chemistry experiments

Virtual labs have been gaining popularity over the last few years, especially during the worldwide lockdown due to the COVID-19 pandemic. In this study, the suitability of virtual labs for school chemistry experiments is addressed and their effectiveness is compared to traditional physical lab experiments by focusing on physical and human resources, convenience, cost, safety, and time involved as well as topic "matter".

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Antibacterial activity by Dombeya wallichii plant extracts obtained by ultrasound-assisted extraction

Herur et al. | Nov 13, 2023

Antibacterial activity by <em>Dombeya wallichii</em> plant extracts obtained by ultrasound-assisted extraction

Medicinal plants could be a good source of medication to combat antibiotic resistance. Dombeya wallichii, which is commonly called Pink Ball Tree in the family Sterculiaceae, has been documented to have medicinal potential. We observed the highest antibacterial activity in the stem extracts, followed by leaf and bark extracts. The extracts were more effective against tested Gram-positive bacteria when compared with Gram-negative strains.

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