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Quantifying natural recovery of dopamine deficits induced by chronic stress

Josyula et al. | Oct 27, 2025

Quantifying natural recovery of dopamine deficits induced by chronic stress
Image credit: Shawn Day

Here the authors investigated the natural recovery of stress-induced dopamine-related gene deficits in C. elegans by measuring the expression of cat-2 (dopamine biosynthesis) and sod-2 (oxidative stress) following exposure to starvation or hydrocortisone. They found that the reversibility of sod-2 and the expression of cat-2 were highly dependent on the type and severity of the stressor, suggesting that the body's natural ability to recover from dopamine dysfunction has biological limitations.

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The effect of economic downturns on the frequency of mass shootings

Bhupathi et al. | Jul 11, 2025

The effect of economic downturns on the frequency of mass shootings

Researching gun violence and mass shootings in the U.S. is difficult due to the lack of consistent data collection. Some studies have linked mass shootings to personal financial stress, but little formal research exists on the impact of broader economic conditions. This study hypothesized an inverse relationship between mass shootings and economic performance, using the S&P 500 and unemployment rate as indicators.

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Analyzing market dynamics and optimizing sales performance with machine learning

Kamat et al. | May 31, 2025

Analyzing market dynamics and optimizing sales performance with machine learning

This study uses interpretable machine learning models, lasso and ridge regression with Shapley analysis, to identify key sales drivers for Corporación Favorita, Ecuador’s largest grocery chain. The results show that macroeconomic factors, especially labor force size, have the greatest impact on sales, though geographic and seasonal variables like city altitude and holiday proximity also play important roles. These insights can help businesses focus on the most influential market conditions to enhance competitiveness and profitability.

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Implication of education levels on gender wage gap across states in the United States and Puerto Rico

Dash et al. | Apr 16, 2025

Implication of education levels on gender wage gap across states in the United States and Puerto Rico

Here the authors examined the relationship between education levels and the gender wage gap (GWG) in the US and Puerto Rico from 2010 to 2022, hypothesizing that higher education would correlate with a lower GWG. Their analysis of income data revealed an inverse correlation, where higher education levels were associated with reduced gender wage disparities, suggesting that policies aimed at closing the gender gap in higher education could promote socioeconomic equality.

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